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Therapy Name PLB1003
Synonyms
Therapy Description

PLB1003 is a small molecule inhibitor of Alk that potentially leads to tumor growth inhibition (Journal of Thoracic Oncology, Volume 14, Issue 10, S651).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
PLB1003 PLB 1003|PLB-1003 ALK Inhibitor 32 PLB1003 is a small molecule inhibitor of Alk that potentially leads to tumor growth inhibition (Journal of Thoracic Oncology, Volume 14, Issue 10, S651).

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
ALK rearrange lung non-small cell carcinoma predicted - sensitive PLB1003 Phase I Actionable In a Phase Ia trial, PLB1003 demonstrated safety and preliminary efficacy, resulted in a disease control rate of 86% (12/14, 10 partial response, 2 stable disease) in patients with ALK-rearranged non-small cell lung cancer who progressed on or did not tolerate previous treatment (Journal of Thoracic Oncology, Volume 14, Issue 10, S651). detail...

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries


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