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Therapy Name INBRX-106
Synonyms
Therapy Description

INBRX-106 (ES 102) is a hexavalent antibody that binds to the TNFRSF4 (OX40) receptor, resulting in clustering and activation of TNFRSF4 (OX40), and potentially leading to activation of immune response and tumor cell killing (NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
INBRX-106 INBRX106|INBRX 106|ES 102|ES-102|ES102 OX40 Antibody 14 INBRX-106 (ES 102) is a hexavalent antibody that binds to the TNFRSF4 (OX40) receptor, resulting in clustering and activation of TNFRSF4 (OX40), and potentially leading to activation of immune response and tumor cell killing (NCI Drug Dictionary).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04198766 Phase I INBRX-106 INBRX-106 + Pembrolizumab Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) Recruiting USA 0


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