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Therapy Name | GAd-209-FSP + MVA-209-FSP |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
GAd-209-FSP | GAd-209-FSP is a great ape adenovirus (GAd) priming vaccine that encodes neoantigens derived from frameshift peptides (FSP), which potentially stimulates immune response leading to tumor cell lysis (NCI Drug Dictionary). | |||
MVA-209-FSP | MVA-209-FSP is a neoantigen booster vaccine against frameshift peptides found in mismatch repair deficient and MSI-high tumors (NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT04041310 | Phase I | GAd-209-FSP + MVA-209-FSP | Nous-209 Genetic Vaccine for the Treatment of Microsatellite Unstable Solid Tumors | Recruiting | USA | ITA | GBR | ESP | CAN | BEL | 0 |