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| Therapy Name | GAd-209-FSP + MVA-209-FSP |
| Synonyms | |
| Therapy Description | |
| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| GAd-209-FSP | GAd-209-FSP is a great ape adenovirus (GAd) priming vaccine that encodes neoantigens derived from frameshift peptides (FSP), which potentially stimulates immune response leading to tumor cell lysis (NCI Drug Dictionary). | |||
| MVA-209-FSP | MVA-209-FSP is a neoantigen booster vaccine against frameshift peptides found in mismatch repair deficient and MSI-high tumors (NCI Drug Dictionary). |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04041310 | Phase I | GAd-209-FSP + MVA-209-FSP | Nous-209 Genetic Vaccine for the Treatment of Microsatellite Unstable Solid Tumors | Active, not recruiting | USA | ITA | GBR | ESP | CAN | BEL | 0 |