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Therapy Name P10s-PADRE
Synonyms
Therapy Description

P10s-PADRE is a peptide vaccine comprised of a carbohydrate mimetic-peptide (P10s) and a pan-T-cell epitope (PADRE), which mimics the ganglioside G2 and LeY antigens, thereby potentially inducing the production of antibodies and leading to reduced cell viability and increased apoptosis (PMID: 29228761, PMID: 32582547).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
P10s-PADRE P10s-PADRE is a peptide vaccine comprised of a carbohydrate mimetic-peptide (P10s) and a pan-T-cell epitope (PADRE), which mimics the ganglioside G2 and LeY antigens, thereby potentially inducing the production of antibodies and leading to reduced cell viability and increased apoptosis (PMID: 29228761, PMID: 32582547).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02229084 Phase Ib/II Montanide ISA 51 + P10s-PADRE P10s-PADRE Vaccination of High Risk Breast Cancer Patients Completed USA 0


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