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Therapy Detail
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| Therapy Name | GGTI-2418 |
| Synonyms | |
| Therapy Description |
GGTI-2418 is a selective inhibitor of GGTase I, leading to inhibition of protein geranylgeranylation, cell cycle arrest, and potentially inhibition of tumor growth (PMID: 19204084). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| GGTI-2418 | PTX-100 | GGTI-2418 is a selective inhibitor of GGTase I, leading to inhibition of protein geranylgeranylation, cell cycle arrest, and potentially inhibition of tumor growth (PMID: 19204084). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT03900442 | Phase I | GGTI-2418 | Phase 1 Study of PTX-100 in Patients With Advanced Malignancies | Active, not recruiting | AUS | 0 |
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