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Therapy Name | GGTI-2418 |
Synonyms | |
Therapy Description |
GGTI-2418 is a selective inhibitor of GGTase I, leading to inhibition of protein geranylgeranylation, cell cycle arrest, and potentially inhibition of tumor growth (PMID: 19204084). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
GGTI-2418 | PTX-100 | GGTI-2418 is a selective inhibitor of GGTase I, leading to inhibition of protein geranylgeranylation, cell cycle arrest, and potentially inhibition of tumor growth (PMID: 19204084). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT03900442 | Phase I | GGTI-2418 | Phase 1 Study of PTX-100 in Patients With Advanced Malignancies | Active, not recruiting | AUS | 0 |