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Therapy Name BDC-1001
Synonyms
Therapy Description

BDC-1001 is an antibody conjugate comprising an ERBB2 (HER2)-targeting antibody linked to a TLR 7/8 agonist, which may enhance antitumor immune response (J Clin Oncol 41, 2023 (suppl 16; abstr 2538)).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
BDC-1001 BDC 1001|BDC1001 HER2 (ERBB2) Antibody 76 BDC-1001 is an antibody conjugate comprising an ERBB2 (HER2)-targeting antibody linked to a TLR 7/8 agonist, which may enhance antitumor immune response (J Clin Oncol 41, 2023 (suppl 16; abstr 2538)).

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05954143 Phase II BDC-1001 + Pertuzumab BDC-1001 Trial of BDC-1001 +/- Pertuzumab in Subjects With HER2-Positive Metastatic Breast Cancer Active, not recruiting USA | ESP 0
NCT04278144 Phase I BDC-1001 + Pembrolizumab BDC-1001 A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors Active, not recruiting USA | FRA | ESP 1


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