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Therapy Detail
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| Therapy Name | BDC-1001 |
| Synonyms | |
| Therapy Description |
BDC-1001 is an antibody conjugate comprising an ERBB2 (HER2)-targeting antibody linked to a TLR 7/8 agonist, which may enhance antitumor immune response (J Clin Oncol 41, 2023 (suppl 16; abstr 2538)). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| BDC-1001 | BDC 1001|BDC1001 | HER2 (ERBB2) Antibody 77 | BDC-1001 is an antibody conjugate comprising an ERBB2 (HER2)-targeting antibody linked to a TLR 7/8 agonist, which may enhance antitumor immune response (J Clin Oncol 41, 2023 (suppl 16; abstr 2538)). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05954143 | Phase II | BDC-1001 + Pertuzumab BDC-1001 | Trial of BDC-1001 +/- Pertuzumab in Subjects With HER2-Positive Metastatic Breast Cancer | Terminated | USA | ESP | 0 |
| NCT04278144 | Phase I | BDC-1001 + Pembrolizumab BDC-1001 | A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors | Terminated | USA | FRA | ESP | 1 |
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