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Therapy Name IOA-244
Synonyms
Therapy Description

IOA-244 is a selective PIK3CD inhibitor, which potentially modulates the tumor microenvironment, leading to an antitumor immune response, and inhibits cell proliferation (PMID: 37066023).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
IOA-244 IOA 244|roginolisib|IOA244 PIK3CD inhibitor 27 IOA-244 is a selective PIK3CD inhibitor, which potentially modulates the tumor microenvironment, leading to an antitumor immune response, and inhibits cell proliferation (PMID: 37066023).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04328844 Phase I IOA-244 A Study to Assess a PI3Kdelta Inhibitor (IOA-244) in Patients With Metastatic Cancers Active, not recruiting ITA | GBR 0


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