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Therapy Name | TAK-169 |
Synonyms | |
Therapy Description |
TAK-169 is an engineered toxin body comprising a fragment of a CD38 antibody fused to Shiga-like toxin A-subunit (SLTA) that inactivates ribosomes, which potentially inhibits protein synthesis leading to killing of CD38-expressing cancer cells and tumor regression (Cancer Res 2019;79(13 Suppl):Abstract nr 2384). |