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Therapy Name | MOv19-BBz CAR T cells |
Synonyms | |
Therapy Description |
MOv19-BBz CAR T cells are human T cells engineered to express a folate receptor-alpha coupled to CD3z in tandem with CD137 (4-1BB), which may lead to persistent anti-tumor immune response (PMID: 21546571). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
MOv19-BBz CAR T cells | MOv19-BBz CAR T cells are human T cells engineered to express a folate receptor-alpha coupled to CD3z in tandem with CD137 (4-1BB), which may lead to persistent anti-tumor immune response (PMID: 21546571). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT03585764 | Phase I | MOv19-BBz CAR T cells | MOv19-BBz CAR T Cells in aFR Expressing Recurrent High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer | Terminated | USA | 0 |