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Therapy Name CPI-818
Synonyms
Therapy Description

CPI-818 inhibits IL-2 inducible T-cell kinase (ITK), which may lead to inhibition of TCR signaling and growth of T cells (Cancer Res 2019;79(13 Suppl):Abstract nr 1313).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
CPI-818 CPI818|CPI 818|Soquelitinib CPI-818 inhibits IL-2 inducible T-cell kinase (ITK), which may lead to inhibition of TCR signaling and growth of T cells (Cancer Res 2019;79(13 Suppl):Abstract nr 1313).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03952078 Phase I CPI-818 A Dose Escalation Study Evaluating CPI-818 in Relapsed/Refractory T-Cell Lymphoma Active, not recruiting USA | AUS 2
NCT06561048 Phase III Pralatrexate CPI-818 Belinostat Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma Recruiting USA 0


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