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Therapy Name ASP1650
Synonyms
Therapy Description

ASP1650 is a monoclonal antibody that targets Claudin 6 (CLDN6), which potentially induces antibody-dependent cell-mediated cytotoxicity and complement-mediated cytotoxicity against tumor cells expressing CLDN6 (Journal of Clinical Oncology 2020 38:6_suppl, TPS424).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
ASP1650 ASP 1650|ASP-1650|IMAB027|Anti-CLDN6 Mab ASP1650 CLDN6 Antibody 8 ASP1650 is a monoclonal antibody that targets Claudin 6 (CLDN6), which potentially induces antibody-dependent cell-mediated cytotoxicity and complement-mediated cytotoxicity against tumor cells expressing CLDN6 (Journal of Clinical Oncology 2020 38:6_suppl, TPS424).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03760081 Phase II ASP1650 A Study to Assess the Safety and Efficacy of ASP1650, a Monoclonal Antibody Targeting Claudin 6 (CLDN6), in Male Subjects With Incurable Platinum Refractory Germ Cell Tumors Completed USA 0


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