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Therapy Name | Autologous CMV-specific CTLs + Temozolomide |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
Autologous CMV-specific CTLs | Autologous cytomegalovirus-specific cytotoxic T-lymphocytes | Autologous CMV-specific CTLs are patient-derived cytotoxic T-lymphocytes (CTLs) that are reactive to cytomegalovirus (CMV), which potentially increase immune response to CMV-related tumors (PMID: 22421947). | ||
Temozolomide | Temodar | Methazolastone|TMZ | Chemotherapy - Alkylating 18 | Temodar (temozolomide) is a dacarbazine analog and cytotoxic alkylating agent (NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT02661282 | Phase Ib/II | Autologous CMV-specific CTLs + Temozolomide | Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With Glioblastoma | Completed | USA | 0 |