Therapy Detail
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| Therapy Name | C134-HSV-1 |
| Synonyms | |
| Therapy Description |
C134-HSV-1 is an oncolytic HSV/HCMV chimeric virus that potentially induces tumor cell death and anti-tumor immune response (PMID: 29216507). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| C134-HSV-1 | C134|C-134|C 134|HSV-1 C134 | C134-HSV-1 is an oncolytic HSV/HCMV chimeric virus that potentially induces tumor cell death and anti-tumor immune response (PMID: 29216507). |
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT03657576 | Phase I | C134-HSV-1 | Trial of C134 in Patients With Recurrent GBM (C134-HSV-1) | Active, not recruiting | USA | 0 |
| NCT06614855 | Phase I | C134-HSV-1 | A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant Glioma | Active, not recruiting | USA | 0 |
| NCT06193174 | Phase I | C134-HSV-1 | Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1) | Enrolling by invitation | USA | 0 |
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