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Therapy Name C134-HSV-1
Synonyms
Therapy Description

C134-HSV-1 is an oncolytic HSV/HCMV chimeric virus that potentially induces tumor cell death and anti-tumor immune response (PMID: 29216507).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
C134-HSV-1 C134|C-134|C 134|HSV-1 C134 C134-HSV-1 is an oncolytic HSV/HCMV chimeric virus that potentially induces tumor cell death and anti-tumor immune response (PMID: 29216507).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06614855 Phase I C134-HSV-1 A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant Glioma Not yet recruiting USA 0
NCT03657576 Phase I C134-HSV-1 Trial of C134 in Patients With Recurrent GBM (C134-HSV-1) Active, not recruiting USA 0
NCT06193174 Phase I C134-HSV-1 Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1) Not yet recruiting USA 0


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