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Therapy Name SGN-CD228A
Synonyms
Therapy Description

SGN-CD228A is an antibody-drug conjugate comprising a CD228 monoclonal antibody linked to eight molecules of the anti-microtubule compound MMAE, which delivers the cytotoxic agent to CD228-expressing tumor cells, potentially resulting in delayed tumor growth (Cancer Res 2019;79(13 Suppl):Abstract nr 2688).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
SGN-CD228A SGNCD228A|SGN CD228A SGN-CD228A is an antibody-drug conjugate comprising a CD228 monoclonal antibody linked to eight molecules of the anti-microtubule compound MMAE, which delivers the cytotoxic agent to CD228-expressing tumor cells, potentially resulting in delayed tumor growth (Cancer Res 2019;79(13 Suppl):Abstract nr 2688).

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04042480 Phase I SGN-CD228A A Study of SGN-CD228A in Advanced Solid Tumors Terminated USA | ITA | GBR | FRA | ESP 0


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