Therapy Detail
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| Therapy Name | FOR46 |
| Synonyms | |
| Therapy Description |
FOR46 (FG-3246) is an antibody-drug conjugate (ADC) comprising a CD46 monoclonal antibody linked to MMAE, which potentially inhibits tumor growth (PMID: 40138611). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| FOR46 | FOR-46|ADC FOR46|CD46-ADC FOR46|FG-3246|FG3246 | FOR46 (FG-3246) is an antibody-drug conjugate (ADC) comprising a CD46 monoclonal antibody linked to MMAE, which potentially inhibits tumor growth (PMID: 40138611). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT03575819 | Phase I | FOR46 | A Phase 1 Study of FOR46 in Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC) | Completed | USA | 0 |
| NCT06842498 | Phase II | FOR46 | A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC) | Recruiting | USA | 0 |
| NCT03650491 | Phase I | FOR46 | A Study of FOR46 in Patients With Relapsed or Refractory Multiple Myeloma (RRMM) | Completed | USA | 0 |
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