Therapy Detail
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| Therapy Name | RGX202 |
| Synonyms | |
| Therapy Description |
RGX202 is an SLC6A8 inhibitor that blocks the uptake of phosphocreatine, thereby potentially reducing ATP synthesis and resulting in the inhibition of tumor growth and metastasis (J Clin Oncol 38, no. 15_suppl (May 20, 2020) 3504-3504). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| RGX202 | RGX-202-01|RGX-202|RGX 202|Ompenaclid | RGX202 is an SLC6A8 inhibitor that blocks the uptake of phosphocreatine, thereby potentially reducing ATP synthesis and resulting in the inhibition of tumor growth and metastasis (J Clin Oncol 38, no. 15_suppl (May 20, 2020) 3504-3504). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT03597581 | Phase I | RGX202 Fluorouracil + Irinotecan + Leucovorin + RGX202 Bevacizumab + Fluorouracil + Irinotecan + Leucovorin + RGX202 | A Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer | Completed | USA | 0 |
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