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Therapy Detail

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Therapy Name RGX202
Synonyms
Therapy Description

RGX202 is an SLC6A8 inhibitor that blocks the uptake of phosphocreatine, thereby potentially reducing ATP synthesis and resulting in the inhibition of tumor growth and metastasis (J Clin Oncol 38, no. 15_suppl (May 20, 2020) 3504-3504).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
RGX202 RGX-202-01|RGX-202|RGX 202|Ompenaclid RGX202 is an SLC6A8 inhibitor that blocks the uptake of phosphocreatine, thereby potentially reducing ATP synthesis and resulting in the inhibition of tumor growth and metastasis (J Clin Oncol 38, no. 15_suppl (May 20, 2020) 3504-3504).

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03597581 Phase I RGX202 Fluorouracil + Irinotecan + Leucovorin + RGX202 Bevacizumab + Fluorouracil + Irinotecan + Leucovorin + RGX202 A Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer Completed USA 0


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