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Therapy Name CYNK-001
Synonyms
Therapy Description

CYNK-001 (taniraleucel) consists of allogeneic CD56+/CD3- natural killer cells expanded from CD34-positive placental stem cells, which may induce cytotoxicity against tumor cells and potentially demonstrates anti-tumor activity (Neuro-Oncology, Vol. 21, Issue Suppl_6, Nov. 2019, Page vi85, EXTH-16).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
CYNK-001 Taniraleucel|CYNK001|CYNK 001 CYNK-001 (taniraleucel) consists of allogeneic CD56+/CD3- natural killer cells expanded from CD34-positive placental stem cells, which may induce cytotoxicity against tumor cells and potentially demonstrates anti-tumor activity (Neuro-Oncology, Vol. 21, Issue Suppl_6, Nov. 2019, Page vi85, EXTH-16).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04309084 Phase Ib/II CYNK-001 Natural Killer Cell (CYNK-001) Infusions in Adults With Multiple Myeloma Active, not recruiting USA 0
NCT04310592 Phase I Cyclophosphamide + Fludarabine CYNK-001 Natural Killer Cell (CYNK-001) Infusions in Adults With AML (CYNK001AML01) Recruiting USA 0
NCT05218408 Phase Ib/II Cyclophosphamide + Fludarabine CYNK-001 CYNK-001 IV and IC in Combination With IL2 in Surgical Eligible Recurrent GBM With IDH-1 Wild Type (CYNK001GBM02) Withdrawn 0


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