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Therapy Name Icatolimab
Synonyms
Therapy Description

Icatolimab (JS004) is a humanized monoclonal antibody that binds to B- and T-lymphocyte attenuator (BTLA) and activates T-cells, thereby potentially resulting in the activation of antitumor immune response (J Clin Oncol 40, no. 16_suppl (June 01, 2022) 2643).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Icatolimab JS004|JS-004|JS 004|TAB004|TAB-004|TAB 004|Tifcemalimab Icatolimab (JS004) is a humanized monoclonal antibody that binds to B- and T-lymphocyte attenuator (BTLA) and activates T-cells, thereby potentially resulting in the activation of antitumor immune response (J Clin Oncol 40, no. 16_suppl (June 01, 2022) 2643).

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04137900 Phase I Icatolimab Safety, Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) for Injection in Subjects With Advanced Malignancies Recruiting USA 0


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