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| NCT ID | NCT03635567 |
| Title | Efficacy and Safety Study of First-line Treatment With Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Women With Persistent, Recurrent, or Metastatic Cervical Cancer (MK-3475-826/KEYNOTE-826) |
| Recruitment | Completed |
| Gender | female |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme Corp. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | ITA | ISR | FRA | ESP | DEU | CAN | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Alaska Women's Cancer Care ( Site 1770) | Anchorage | Alaska | 99508 | United States | Details | |
| Arizona Oncology Associates, PC- HAL ( Site 8005) | Phoenix | Arizona | 85016 | United States | Details | |
| UC Irvine Health ( Site 1796) | Orange | California | 92868 | United States | Details | |
| Smilow Cancer Hospital at Yale New Haven ( Site 1809) | New Haven | Connecticut | 06510 | United States | Details | |
| H. Lee Moffitt Cancer Center and Research Institute ( Site 1754) | Tampa | Florida | 33612 | United States | Details | |
| Georgia Cancer Center at Augusta University ( Site 1767) | Augusta | Georgia | 30912 | United States | Details | |
| Barbara Ann Karmanos Cancer Institute ( Site 1785) | Detroit | Michigan | 48201 | United States | Details | |
| Henry Ford Health System ( Site 1810) | Detroit | Michigan | 48202 | United States | Details | |
| Washington University School of Medicine ( Site 1779) | Saint Louis | Missouri | 63110 | United States | Details | |
| Cancer Institute of New Jersey at University Hospital ( Site 1762) | Newark | New Jersey | 07103 | United States | Details | |
| Holy Name Medical Center ( Site 1776) | Teaneck | New Jersey | 07666 | United States | Details | |
| Mount Sinai Chelsea ( Site 1760) | New York | New York | 10011 | United States | Details | |
| Columbia University Medical Center ( Site 1800) | New York | New York | 10032 | United States | Details | |
| OSU Wexner Medical Center ( Site 1817) | Hilliard | Ohio | 43026 | United States | Details | |
| University of Oklahoma- Stephenson Oklahoma Cancer Center ( Site 1784) | Oklahoma City | Oklahoma | 73104 | United States | Details | |
| Oklahoma Cancer Specialists and Research Institute, LLC ( Site 1768) | Tulsa | Oklahoma | 74146 | United States | Details | |
| MUSC Hollings Cancer Center ( Site 1819) | Charleston | South Carolina | 29425 | United States | Details | |
| West Cancer Center - East Campus ( Site 1763) | Germantown | Tennessee | 38138 | United States | Details | |
| Texas Oncology-San Antonio Medical Center ( Site 8001) | San Antonio | Texas | 78240 | United States | Details | |
| Seattle Cancer Care Alliance ( Site 1777) | Seattle | Washington | 98109 | United States | Details | |
| Centro de Oncologia e Investigacion Buenos Aires COIBA ( Site 1006) | Berazategui | Buenos Aires | B1884BBF | Argentina | Details | |
| Hospital Aleman ( Site 1005) | Buenos Aires | C1118AAT | Argentina | Details | ||
| Hospital de Oncologia Angel Roffo ( Site 1003) | Buenos Aires | C1417DTB | Argentina | Details | ||
| Instituto Medico Especializado Alexander Fleming ( Site 1009) | Buenos Aires | C1426ANZ | Argentina | Details | ||
| Centro Oncologico Riojano Integral ( Site 1004) | La Rioja | F5300COE | Argentina | Details | ||
| Centro Medico San Roque ( Site 1001) | Tucuman | T4000IAK | Argentina | Details | ||
| Royal North Shore Hospital ( Site 1514) | St Leonards | New South Wales | 2065 | Australia | Details | |
| Mater Misericordiae Ltd Mater Cancer Care Centre ( Site 1521) | South Brisbane | Queensland | 4101 | Australia | Details | |
| Flinders Medical Centre ( Site 1513) | Bedford Park | South Australia | 5042 | Australia | Details | |
| St John of God Subiaco Hospital ( Site 1512) | Subiaco | Western Australia | 6008 | Australia | Details | |
| Monash Health-Monash Medical Centre ( Site 1519) | Clayton | 3168 | Australia | Details | ||
| Tom Baker Cancer Centre ( Site 1728) | Calgary | Alberta | T2N 4N2 | Canada | Details | |
| BC Cancer-Kelowna - Sindi Ahluwalia Hawkins Centre ( Site 1734) | Kelowna | British Columbia | V1Y 5L3 | Canada | Details | |
| BC Cancer - Vancouver Center ( Site 1722) | Vancouver | British Columbia | V5Z 4E6 | Canada | Details | |
| CancerCare Manitoba ( Site 1725) | Winnipeg | Manitoba | R3E 0V9 | Canada | Details | |
| Queen Elizabeth II Health Sciences Centre ( Site 1731) | Halifax | Nova Scotia | B3H 2Y9 | Canada | Details | |
| Juravinski Cancer Centre ( Site 1735) | Hamilton | Ontario | L8V 5C2 | Canada | Details | |
| London Regional Cancer Program - London HSC ( Site 1723) | London | Ontario | N6A 5W9 | Canada | Details | |
| The Ottawa Hospital Cancer Centre ( Site 1736) | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| Sunnybrook Research Institute ( Site 1733) | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| Princess Margaret Cancer Centre ( Site 1732) | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| CIUSSS du Saguenay-Lac-St-Jean ( Site 1729) | Chicoutimi | Quebec | G7H 5H6 | Canada | Details | |
| CIUSSS de l Est de L Ile de Montreal - Hopital Maisonneuve-Rosemont ( Site 1726) | Montreal | Quebec | H1T 2M4 | Canada | Details | |
| Centre Hospitalier de l Universite de Montreal - CHUM ( Site 1721) | Montreal | Quebec | H2X 3E4 | Canada | Details | |
| CIUSSS de l Estrie - CHUS - Centre Hosp. Univ. Sherbrooke ( Site 1730) | Sherbrooke | Quebec | J1H 5N4 | Canada | Details | |
| CHU de Quebec-Universite Laval-Hotel Dieu de Quebec ( Site 1724) | Quebec | G1R 2J6 | Canada | Details | ||
| Oncocentro ( Site 1065) | Vina del Mar | Valparaiso | 2520598 | Chile | Details | |
| Fundacion Arturo Lopez Perez FALP ( Site 1061) | Santiago | 7500921 | Chile | Details | ||
| Sociedad Oncovida S.A. ( Site 1069) | Santiago | 7510032 | Chile | Details | ||
| Centro de Cancer Nuestra Senora de la Esperanza ( Site 1063) | Santiago | 8330024 | Chile | Details | ||
| Instituto Clinico Oncologico del Sur ( Site 1062) | Temuco | 4810469 | Chile | Details | ||
| Sociedad de Oncologia y Hematologia del Cesar Ltda. ( Site 1103) | Valledupar | Cesar | 200001 | Colombia | Details | |
| Instituto Nacional de Cancerologia E.S.E ( Site 1095) | Bogota | Cundinamarca | 111511 | Colombia | Details | |
| Hemato Oncologos S.A. ( Site 1100) | Cali | Valle | 760046 | Colombia | Details | |
| Biomelab S A S ( Site 1104) | Barranquilla | 080002 | Colombia | Details | ||
| Oncomedica S.A. ( Site 1098) | Monteria | 230002 | Colombia | Details | ||
| Instituto Cancerologico de Narino Ltda ( Site 1097) | Pasto | 520001 | Colombia | Details | ||
| Centre Jean Perrin ( Site 1181) | Clermont Ferrand | 63011 | France | Details | ||
| Institut Paoli Calmettes ( Site 1182) | Marseille | 13009 | France | Details | ||
| Groupe Hospitalier Broca Cochin Hotel Dieu ( Site 1183) | Paris | 75014 | France | Details | ||
| Centre Eugene Marquis ( Site 1187) | Rennes | 35042 | France | Details | ||
| Institut Curie - Centre Rene Huguenin ( Site 1185) | Saint-Cloud | 92210 | France | Details | ||
| Universitaetsklinikum Carl Gustav Carus ( Site 1211) | Dresden | 01307 | Germany | Details | ||
| Universitaetsklinikum Duesseldorf ( Site 1220) | Duesseldorf | 40225 | Germany | Details | ||
| Universitatsklinikum Essen AoR ( Site 1213) | Essen | 45147 | Germany | Details | ||
| Universitatsklinikum Hamburg-Eppendorf ( Site 1212) | Hamburg | 20251 | Germany | Details | ||
| Gynoncological Practice Lueck. Schrader. Noeding ( Site 1224) | Hannover | 30177 | Germany | Details | ||
| Universitaetsklinikum Schleswig-Holstein Campus Kiel ( Site 1214) | Kiel | 24105 | Germany | Details | ||
| Rotkreuzklinikum Muenchen gGmbH. Studienzentrale Frauenklinik ( Site 1225) | Muenchen | 80637 | Germany | Details | ||
| Klinikum Oldenburg AoeR ( Site 1218) | Oldenburg | 26133 | Germany | Details | ||
| Universitaet Regensburg ( Site 1221) | Regensburg | 93053 | Germany | Details | ||
| Soroka Medical Center ( Site 1363) | Beer-Sheva | 8410101 | Israel | Details | ||
| Rambam Medical Center ( Site 1364) | Haifa | 3525408 | Israel | Details | ||
| Shaare Zedek Medical Center ( Site 1366) | Jerusalem | 9103102 | Israel | Details | ||
| Hadassah Medical Center. Ein Kerem ( Site 1367) | Jerusalem | 9112001 | Israel | Details | ||
| Rabin Medical Center ( Site 1365) | Petah Tikva | 4941492 | Israel | Details | ||
| Chaim Sheba Medical Center ( Site 1361) | Ramat Gan | 5265601 | Israel | Details | ||
| Sourasky Medical Center ( Site 1362) | Tel Aviv | 6423906 | Israel | Details | ||
| Centro di Riferimento Oncologico de Aviano Istituto Nazionale Tumori ( Site 1243) | Aviano | 33081 | Italy | Details | ||
| A.O. Universitaria Policlinico S. Orsola-Malpighi ( Site 1245) | Bolgna | 40138 | Italy | Details | ||
| Istituto Nazionale Tumori ( Site 1251) | Milano | 20133 | Italy | Details | ||
| Istituto Europeo di Oncologia ( Site 1250) | Milano | 20141 | Italy | Details | ||
| Istituto Nazionale Tumori IRCCS Fondazione Pascale ( Site 1242) | Napoli | 80131 | Italy | Details | ||
| Policlinico Universitario -Agostino Gemelli ( Site 1241) | Roma | 00168 | Italy | Details | ||
| The Jikei University Kashiwa Hospital ( Site 1701) | Kashiwa | Chiba | 277-8567 | Japan | Details | |
| National Cancer Center Hospital East ( Site 1704) | Kashiwa | Chiba | 277-8577 | Japan | Details | |
| Ehime University Hospital ( Site 1693) | Toon | Ehime | 791-0295 | Japan | Details | |
| Kurume University Hospital ( Site 1692) | Kurume | Fukuoka | 830-0011 | Japan | Details | |
| National Hospital Organization Hokkaido Cancer Center ( Site 1700) | Sapporo | Hokkaido | 003-0804 | Japan | Details | |
| Hyogo Cancer Center ( Site 1705) | Akashi | Hyogo | 673-8558 | Japan | Details | |
| Iwate Medical University Hospital ( Site 1695) | Shiwa-gun | Iwate | 028-3695 | Japan | Details | |
| University of the Ryukyus Hospital ( Site 1706) | Nakagami-gun | Okinawa | 903-0215 | Japan | Details | |
| Saitama Medical University International Medical Center ( Site 1691) | Hidaka | Saitama | 350-1298 | Japan | Details | |
| Shizuoka Cancer Center Hospital and Research Institute ( Site 1703) | Sunto-gun | Shizuoka | 411-8777 | Japan | Details | |
| National Cancer Center Hospital ( Site 1702) | Tokyo | 104-0045 | Japan | Details | ||
| The Jikei University Hospital ( Site 1697) | Tokyo | 105-8471 | Japan | Details | ||
| The Cancer Institute Hospital of JFCR ( Site 1698) | Tokyo | 135-8550 | Japan | Details | ||
| Keio University Hospital ( Site 1699) | Tokyo | 160-8582 | Japan | Details | ||
| Keimyung University Dongsan Medical Center ( Site 1603) | Daegu | 42601 | Korea, Republic of | Details | ||
| Seoul National University Hospital ( Site 1602) | Seoul | 03080 | Korea, Republic of | Details | ||
| Asan Medical Center ( Site 1601) | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center ( Site 1604) | Seoul | 06351 | Korea, Republic of | Details | ||
| Medical Care and Research S.A. de C.V. ( Site 1135) | Merida | Yucatan | 97070 | Mexico | Details | |
| Centro Estatal de Cancerologia de Chihuahua ( Site 1123) | Chihuahua | 31000 | Mexico | Details | ||
| Consultorio de Medicina Especializada del Sector Privado ( Site 1129) | Ciudad de Mexico | 03100 | Mexico | Details | ||
| CRYPTEX Investigacion Clinica S.A. de C.V. ( Site 1127) | Ciudad de Mexico | 06100 | Mexico | Details | ||
| Instituto Nacional de Cancerologia. ( Site 1130) | Mexico | 14080 | Mexico | Details | ||
| Centro de Urologia Avanzada del Noreste S.A. de C.V. ( Site 1125) | San Pedro Garza Garcia | 66269 | Mexico | Details | ||
| Faicic S de RL de CV ( Site 1133) | Veracruz | 91900 | Mexico | Details | ||
| Hospital de Alta Complejidad de La Libertad Virgen de La Puerta ( Site 1152) | Trujillo | La Libertad | 13006 | Peru | Details | |
| Centro Medico Monte Carmelo ( Site 1156) | Arequipa | 04001 | Peru | Details | ||
| Hospital Nacional Guillermo Almenara Irigoyen ( Site 1158) | Lima | 15033 | Peru | Details | ||
| Instituto de Oncologia y Radioterapia Clinica Ricardo Palma ( Site 1157) | Lima | 15036 | Peru | Details | ||
| Instituto Nacional de Enfermedades Neoplasicas ( Site 1153) | Lima | 15038 | Peru | Details | ||
| Hospital Nacional Arzobispo Loayza ( Site 1159) | Lima | 15082 | Peru | Details | ||
| Hospital Nacional Maria Auxiliadora ( Site 1155) | Lima | 15801 | Peru | Details | ||
| Republican Clinical Oncology Dispensary of Tatarstan MoH ( Site 1331) | Kazan | 420029 | Russian Federation | Details | ||
| FSBI National Medical Oncology Research Center n.a. N.N. Blokhina ( Site 1334) | Moscow | 115478 | Russian Federation | Details | ||
| Medical Rehabilitation Center ( Site 1337) | Moscow | 125367 | Russian Federation | Details | ||
| Novosibirsk Regional Clinical Oncology Dispensary ( Site 1358) | Novosibirsk | 630108 | Russian Federation | Details | ||
| Municipal Clinical Oncology Center ( Site 1346) | Saint Petersburg | 198255 | Russian Federation | Details | ||
| National Research Ogarev Mordovia State University ( Site 1347) | Saransk | 430005 | Russian Federation | Details | ||
| National Medical Research Center of Oncology n.a. N. N. Petrov ( Site 1348) | St. Petersburg | 197758 | Russian Federation | Details | ||
| Tomsk Scientific Research Institute of Oncology ( Site 1360) | Tomsk | 634028 | Russian Federation | Details | ||
| Republican Clinical Oncology Dispensary of Republic of Bashkortostan ( Site 1345) | Ufa | 450054 | Russian Federation | Details | ||
| Onkologikoa - Instituto Oncologico de San Sebastian ( Site 1275) | Doniostia - San Sebastian | Guipuzcoa | 20014 | Spain | Details | |
| Hospital Quiron Madrid ( Site 1277) | Pozuelo de Alarcon | Madrid | 28223 | Spain | Details | |
| Hospital Germans Trias i Pujol. ICO de Badalona ( Site 1276) | Badalona | 08916 | Spain | Details | ||
| MD Anderson Cancer Center Madrid ( Site 1273) | Madrid | 28033 | Spain | Details | ||
| Hospital Universitario Virgen Macarena ( Site 1274) | Sevilla | 41009 | Spain | Details | ||
| Kaohsiung Veterans General Hospital ( Site 1632) | Kaohsiung | 813 | Taiwan | Details | ||
| China Medical University Hospital ( Site 1635) | Taichung | 40447 | Taiwan | Details | ||
| Taichung Veterans General Hospital ( Site 1634) | Taichung | 40705 | Taiwan | Details | ||
| Koo Foundation Sun Yat-Sen Cancer Center ( Site 1636) | Taipei | 112 | Taiwan | Details | ||
| Taipei Veterans General Hospital ( Site 1631) | Taipei | 112 | Taiwan | Details | ||
| Chang Gung Medical Foundation. Linkou ( Site 1633) | Taoyuan | 33305 | Taiwan | Details | ||
| Baskent Adana Dr Turgut Noyan Uygulama ve Arastirma Merkezi ( Site 1457) | Adana | 01250 | Turkey | Details | ||
| Hacettepe University Medical Faculty ( Site 1459) | Ankara | 06230 | Turkey | Details | ||
| Baskent Universitesi Ankara Hastanesi ( Site 1451) | Ankara | 06490 | Turkey | Details | ||
| Akdeniz Universitesi Tip Fakultesi ( Site 1453) | Antalya | 07059 | Turkey | Details | ||
| Medeniyet University Goztepe Egitim ve Arastırma Hast. Merdivenkoy ( Site 1458) | Istanbul | 34722 | Turkey | Details | ||
| Ege University Medical Faculty Tulay Aktas Oncology Hospital ( Site 1456) | Izmir | 35040 | Turkey | Details | ||
| Necmettin Erbakan Universitesi Meram Tip Fakultesi Hastanesi ( Site 1452) | Konya | 42080 | Turkey | Details | ||
| City Clinical Hosp.4 of DCC ( Site 1482) | Dnipropetrovsk | 49102 | Ukraine | Details | ||
| MI Precarpathian Clinical Oncology Center ( Site 1487) | Ivano-Frankivsk | 76018 | Ukraine | Details | ||
| Communal non profit enterprise Regional Clinical Oncology Center ( Site 1489) | Kharkiv | 61070 | Ukraine | Details | ||
| National Cancer Institute of the MoH of Ukraine ( Site 1484) | Kyiv | 03022 | Ukraine | Details | ||
| MI Odessa Regional Oncological Centre ( Site 1493) | Odesa | 65055 | Ukraine | Details | ||
| Medical Centre LLC Oncolife ( Site 1485) | Zaporizhzhya | 69104 | Ukraine | Details |