Starting April 21, you’ll be asked to log in or sign up for a free account after viewing 10 content pages each month.
Don’t worry—creating an account is quick and easy, and it comes with added benefits! Once logged in, you’ll not only continue accessing the content you already enjoy, but you’ll also unlock exclusive features like interactive donut plots for variant protein effects and variant impacts across the gene.
Stay tuned for these updates, and thank you for being part of our community!
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| NCT ID | NCT03899792 |
| Title | A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumors (LIBRETTO-121) |
| Acronym | LIBRETTO-121 |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase Ib/II |
| Variant Requirements | Yes |
| Sponsors | Loxo Oncology, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | child |
| Covered Countries | USA | ITA | GBR | FRA | ESP | DNK | DEU | CAN | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Childrens Hospital of Los Angeles | Los Angeles | California | 90027 | United States | Details | |
| The Children's Hospital for Cancer and Blood Disorders | Aurora | Colorado | 80045 | United States | Details | |
| Nemours Children's Health | Orlando | Florida | 32827 | United States | Details | |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| University of Minnesota Hospital | Minneapolis | Minnesota | 55455 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229-3039 | United States | Details | |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| St. Jude Children's Research Hospital | Memphis | Tennessee | 38105 | United States | Details | |
| University of Texas Southwestern Medical Center at Dallas | Dallas | Texas | 75390-9063 | United States | Details | |
| Texas Childrens Hospital | Houston | Texas | 77025 | United States | Details | |
| Seattle Children's Hospital Research Foundation | Seattle | Washington | 98105 | United States | Details | |
| The Children's Hospital at Westmead | Westmead | New South Wales | 2145 | Australia | Details | |
| Royal Children's Hospital | Melbourne | Victoria | 3052 | Australia | Details | |
| The Hospital for Sick Children | Toronto | Ontario | M5G 1X8 | Canada | Details | |
| Rigshospitalet | Copenhagen | 2200 | Denmark | Details | ||
| Gustave Roussy | Villejuif Cedex | 94805 | France | Details | ||
| Universitätsklinikum Heidelberg | Heidelberg | Baden-Württemberg | 69115 | Germany | Details | |
| Fondazione IRCCS Istituto Nazionale dei Tumori | Milan | Lombardia | 20133 | Italy | Details | |
| Hokkaido University Hospital | Sapporo | Hokkaido | 060-8648 | Japan | Details | |
| National Cancer Center Hospital | Chuo-ku | Tokyo | 104-0045 | Japan | Details | |
| Hiroshima University Hospital | Hiroshima | 734-8551 | Japan | Details | ||
| Kyoto University Hospital | Kyoto | 606-8507 | Japan | Details | ||
| Seoul National University Hospital | Seoul | Korea | 03080 | Korea, Republic of | Details | |
| Hospital Universitari Vall d'Hebron | Barcelona | Barcelona [Barcelona] | 8035 | Spain | Details | |
| University College Hospital - London | London | Greater London | NW1 2BU | United Kingdom | Details |