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| NCT ID | NCT04221945 |
| Title | Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11) |
| Recruitment | Active, not recruiting |
| Gender | female |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme Corp. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | SWE | NOR | ITA | ISR | IRL | HUN | GRC | GBR | FRA | ESP | DEU | CZE | CAN | BRA | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| A.O. Universitaria Policlinico S. Orsola-Malpighi ( Site 0541) | Bologna | 40138 | Italy | Details | ||
| A.O.U. Citta della Salute e della Scienza di Torino ( Site 0535) | Torino | 10126 | Italy | Details | ||
| Acibadem Adana Hastanesi ( Site 0756) | Adana | 01130 | Turkey | Details | ||
| AdventHealth Orlando-AdventHealth Medical Group Gynecological Oncology ( Site 0009) | Orlando | Florida | 32804 | United States | Details | |
| Affiliated Cancer Hospital of Guangxi Medical University ( Site 1036) | Nanning | Guangxi | 530021 | China | Details | |
| Aichi Cancer Center Hospital ( Site 1155) | Nagoya | Aichi | 464-8681 | Japan | Details | |
| Alexandra General Hospital ( Site 0477) | Athens | Attiki | 11528 | Greece | Details | |
| Allegheny Health Network West Penn Hospital-Gynecologic Oncology ( Site 0030) | Pittsburgh | Pennsylvania | 15244 | United States | Details | |
| Anhui Provincial Cancer Hospital ( Site 1007) | Hefei | Anhui | 230031 | China | Details | |
| Anhui Provincial Hospital ( Site 1029) | Hefei | Anhui | 230001 | China | Details | |
| Asan Medical Center ( Site 1062) | Seoul. | Seoul | 05505 | Korea, Republic of | Details | |
| AZ St Lucas ( Site 0349) | Gent | Oost-Vlaanderen | 9000 | Belgium | Details | |
| Baskent Universitesi Ankara Hastanesi ( Site 0754) | Ankara | 06490 | Turkey | Details | ||
| C.I.U. Hopital Ambroise Pare ( Site 0353) | Mons | Hainaut | 7000 | Belgium | Details | |
| Centre Hospitalier de l Universite de Montreal - CHUM ( Site 0101) | Montreal | Quebec | H2X 0A9 | Canada | Details | |
| Centre Hospitalier Lyon Sud ( Site 0413) | Pierre Benite | Rhone | 69310 | France | Details | |
| Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 0 | Quebec City | Quebec | G1J 1Z4 | Canada | Details | |
| Centro de Investigaciones Clinicas de Latinoamerica S.A. - CELAN ( Site 0321) | Guatemala | 01010 | Guatemala | Details | ||
| Centro Investigación del Cáncer James Lind ( Site 0194) | Temuco | Araucania | 4800827 | Chile | Details | |
| Centro Medico Imbanaco de Cali S.A ( Site 0227) | Cali | Valle Del Cauca | 760042 | Colombia | Details | |
| Centro Medico Integral De Cancerología (CEMIC) ( Site 0322) | Quetzaltenango | 09002 | Guatemala | Details | ||
| Centro Medico Monte Carmelo ( Site 0289) | Arequipa | Ariqipa | 04001 | Peru | Details | |
| Chaim Sheba Medical Center ( Site 0814) | Ramat Gan | 5262000 | Israel | Details | ||
| Charite Universitaetsmedizin Berlin ( Site 0442) | Berlin | 13353 | Germany | Details | ||
| Chelyabinsk Regional Clinical Center Oncology and Nuclear Medicine ( Site 0741) | Chelyabinsk | Chelyabinskaya Oblast | 454087 | Russian Federation | Details | |
| Chongqing Cancer Hospital ( Site 1030) | Chongqing | Chongqing | 400030 | China | Details | |
| CHU Jean Minjoz ( Site 0411) | Besancon | Doubs | 25000 | France | Details | |
| Clinica San Gabriel ( Site 0296) | San Miguel | Lima | 15087 | Peru | Details | |
| Complejo Hospitalario de Jaen ( Site 0632) | Jaen | 23007 | Spain | Details | ||
| Cork University Hospital ( Site 0504) | Cork | T12 DC4A | Ireland | Details | ||
| Debreceni Egyetem Klinikai Kozpont ( Site 0845) | Debrecen | 4032 | Hungary | Details | ||
| Ehime University Hospital ( Site 1157) | Toon | Ehime | 790-0295 | Japan | Details | |
| Euromedica General Clinic of Thessaloniki ( Site 0474) | Thessaloniki | 546 45 | Greece | Details | ||
| Fakultni Nemocnice Brno Bohunice ( Site 0912) | Brno | Brno-mesto | 602 00 | Czechia | Details | |
| Fakultni nemocnice Kralovske Vinohrady ( Site 0913) | Praha 10 | 100 34 | Czechia | Details | ||
| Fakultni nemocnice Ostrava ( Site 0909) | Ostrava | Moravskoslezsky Kraj | 708 52 | Czechia | Details | |
| Fondazione Giovanni Pascale Di Napoli ( Site 0544) | Napoli | 80131 | Italy | Details | ||
| Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 0542) | Milano | 20133 | Italy | Details | ||
| Fundacion Centro de Investigacion Clinica CIC ( Site 0231) | Medellin | Antioquia | 050021 | Colombia | Details | |
| Fundacion Valle del Lili ( Site 0230) | Cali | Valle Del Cauca | 760032 | Colombia | Details | |
| GBUZ SPb CRPCstmc(o) ( Site 0746) | Saint Petersburg | Sankt-Peterburg | 197758 | Russian Federation | Details | |
| General Hospital of Patras. St Andrews ( Site 0473) | Patras | Achaia | 262 00 | Greece | Details | |
| Grigoriev Institute for medical Radiology NAMS of Ukraine ( Site 0876) | Kharkiv | Kharkivska Oblast | 61024 | Ukraine | Details | |
| Grupo Angeles SA ( Site 0319) | Guatemala | 01015 | Guatemala | Details | ||
| GZA Sint Augustinus ( Site 0356) | Wilrijk | Antwerpen | 2610 | Belgium | Details | |
| Hadassah Medical Center. Ein Kerem ( Site 0816) | Jerusalem | 9112001 | Israel | Details | ||
| Harbin Medical University Cancer Hospital ( Site 1013) | Harbin | Heilongjiang | 150081 | China | Details | |
| Helse Bergen HF Haukeland Universitetssjukehus ( Site 0601) | Bergen | Hordaland | 5021 | Norway | Details | |
| Hoag Memorial Hospital Presbyterian ( Site 0038) | Newport Beach | California | 92663 | United States | Details | |
| Hokkaido University Hospital ( Site 1163) | Sapporo | Hokkaido | 060-8648 | Japan | Details | |
| Hollings Cancer Center ( Site 0007) | Charleston | South Carolina | 29425 | United States | Details | |
| HonorHealth Research Institute - Biltmore ( Site 8009) | Phoenix | Arizona | 85016 | United States | Details | |
| Hosp Clin Univ de Santiago ( Site 0629) | Santiago de Compostela | La Coruna | 15706 | Spain | Details | |
| Hospital Clinico Universitario Lozano Blesa ( Site 0630) | Zaragoza | 50009 | Spain | Details | ||
| Hospital das Clinicas da UFMG ( Site 0172) | Belo Horizonte | Minas Gerais | 30130-100 | Brazil | Details | |
| Hospital de Alta Complejidad de La Libertad Virgen de La Puerta ( Site 0287) | Trujillo | La Libertad | 13013 | Peru | Details | |
| Hospital de Clínicas de Ribeirão Preto ( Site 0171) | Ribeirão Preto | Sao Paulo | 14048900 | Brazil | Details | |
| Hospital Germans Trias i Pujol-Instituto Catalán de Oncología de Badalona ( Site 0637) | Badalona | Barcelona | 08916 | Spain | Details | |
| Hospital Hygeia ( Site 0478) | Athens | Attiki | 151 23 | Greece | Details | |
| Hospital Nacional Arzobispo Loayza ( Site 0292) | Lima | 15082 | Peru | Details | ||
| Hospital Nacional Daniel Alcides Carrion ( Site 0293) | Callao | Lima | 07021 | Peru | Details | |
| Hospital Nacional Guillermo Almenara Irigoyen ( Site 0291) | Lima | 15082 | Peru | Details | ||
| Hospital Universitari Vall d Hebron ( Site 0634) | Barcelona | 08035 | Spain | Details | ||
| HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID-ONCOLOGIA MEDICA ( Site 0638) | Pozuelo de Alarcon | Madrid | 28223 | Spain | Details | |
| Hunan Cancer Hospital ( Site 1015) | Changsha | Hunan | 233004 | China | Details | |
| I.U. Cerrahpasa Medical Faculty ( Site 0755) | Istambul | Istanbul | 34093 | Turkey | Details | |
| Institut Claudius Regaud ( Site 0417) | Toulouse | Haute-Garonne | 31059 | France | Details | |
| Instituto de Oncologia y Radioterapia Clinica Ricardo Palma ( Site 0290) | Lima | 15036 | Peru | Details | ||
| Instituto Nacional de Cancerologia E.S.E ( Site 0228) | Bogota | Distrito Capital De Bogota | 110321 | Colombia | Details | |
| Instituto Nacional Do Cancer II ( Site 0173) | Rio de Janeiro | 20220-410 | Brazil | Details | ||
| Iram Cancer Research ( Site 0198) | Santiago | Region M. De Santiago | 7630370 | Chile | Details | |
| IRCCS Ospedale San Raffaele ( Site 0539) | Milano | 20132 | Italy | Details | ||
| Istituto di Candiolo - IRCCS ( Site 0546) | Candiolo | Piemonte | 10060 | Italy | Details | |
| Istituto Europeo di Oncologia ( Site 0536) | Milan | Milano | 20141 | Italy | Details | |
| Istituto Nazionale Tumori Regina Elena ( Site 0540) | Rome | Roma | 00144 | Italy | Details | |
| Iwate Medical University Hospital ( Site 1165) | Shiwa-gun | Iwate | 028-3695 | Japan | Details | |
| Japanese Foundation for Cancer Research-Gynecologic Oncology ( Site 1171) | Tokyo | 135-8550 | Japan | Details | ||
| Kagoshima City Hospital ( Site 1166) | Kagoshima | 890-8760 | Japan | Details | ||
| Karmanos Cancer Institute ( Site 0018) | Detroit | Michigan | 48201 | United States | Details | |
| Karolinska Universitetssjukhuset ( Site 0784) | Stockholm | Stockholms Lan | 171 76 | Sweden | Details | |
| Keimyung University Dongsan Medical Center ( Site 1066) | Daegu | Taegu-Kwangyokshi | 42601 | Korea, Republic of | Details | |
| Keio University Hospital ( Site 1170) | Tokyo | 160-8582 | Japan | Details | ||
| Klinikum der Universitaet in Muenchen ( Site 0446) | Muenchen | Bayern | 80336 | Germany | Details | |
| Klinikum Rechts der Isar. Technischen Universitaet Muenchen ( Site 0453) | Muenchen | Bayern | 81675 | Germany | Details | |
| Krasnoyarsk Regional Clinical Oncological Dispensary ( Site 0729) | Krasnoyarsk | Krasnoyarskiy Kray | 660133 | Russian Federation | Details | |
| Kurume University Hospital ( Site 1164) | Kurume | Fukuoka | 830-0011 | Japan | Details | |
| Kyorin University Hospital ( Site 1158) | Mitaka | Tokyo | 181-8611 | Japan | Details | |
| Legacy Good Samaritan Medical Center ( Site 0013) | Portland | Oregon | 97210 | United States | Details | |
| Liga Norte Riograndense Contra o Cancer ( Site 0170) | Natal | Rio Grande Do Norte | 59075-740 | Brazil | Details | |
| Linkou Chang Gung Memorial Hospital ( Site 1097) | Taoyuan | 333 | Taiwan | Details | ||
| Lviv State Oncology Regional Treatment and Diagnostic Center ( Site 0882) | Lviv | Lvivska Oblast | 79031 | Ukraine | Details | |
| Mackay Memorial Hospital ( Site 1094) | Taipei | 104 | Taiwan | Details | ||
| Maharaj Nakorn Chiang Mai Hospital ( Site 1133) | Chiang Mai | 50200 | Thailand | Details | ||
| McGill University Health Centre ( Site 0105) | Montreal | Quebec | H4A 3J1 | Canada | Details | |
| Medi-K Cayala ( Site 0318) | Guatemala | 01016 | Guatemala | Details | ||
| Medizinische Universitat Graz ( Site 0569) | Graz | Steiermark | 8036 | Austria | Details | |
| Medizinische Universitat Innsbruck ( Site 0566) | Innsbruck | Tirol | 6020 | Austria | Details | |
| Medizinische Universität Wien ( Site 0567) | Vienna | Wien | 1090 | Austria | Details | |
| Minnesota Oncology Hematology, PA ( Site 8007) | Minneapolis | Minnesota | 55404 | United States | Details | |
| Monash Health-Monash Medical Centre ( Site 0970) | Clayton | Victoria | 3168 | Australia | Details | |
| MSROI named after P.A. Hertsen branch of FSBI NMRC Radiology ( Site 0722) | Moscow | Moskva | 125284 | Russian Federation | Details | |
| National Cancer Center ( Site 1065) | Goyang-si | Kyonggi-do | 10408 | Korea, Republic of | Details | |
| National Cancer Center Hospital ( Site 1172) | Tokyo | 104-0045 | Japan | Details | ||
| National Cancer Center Hospital East ( Site 1159) | Kashiwa | Chiba | 2778577 | Japan | Details | |
| National Hospital Organization Kyushu Cancer Center ( Site 1167) | Fukuoka | 811-1395 | Japan | Details | ||
| National Hospital Organization Shikoku Cancer Center ( Site 1162) | Matsuyama | Ehime | 791-0280 | Japan | Details | |
| National Medical Research Center of Oncology N.A. N.N. Petrov ( Site 0725) | St. Petersburg | Sankt-Peterburg | 197758 | Russian Federation | Details | |
| National Taiwan University Hospital ( Site 1095) | Taipei | 100 | Taiwan | Details | ||
| Núcleo de Pesquisa Clínica da Rede São Camilo ( Site 0166) | São Paulo | Sao Paulo | 04014-002 | Brazil | Details | |
| OLV Ziekenhuis ( Site 0352) | Aalst | Oost-Vlaanderen | 9300 | Belgium | Details | |
| Oncocentro ( Site 0195) | Vina del Mar | Valparaiso | Chile | Details | ||
| Oncologika S.A. ( Site 0323) | Guatemala | 01010 | Guatemala | Details | ||
| Oncomedica ( Site 0320) | Guatemala | 01010 | Guatemala | Details | ||
| Orszagos Onkologiai Intezet ( Site 0846) | Budapest | 1122 | Hungary | Details | ||
| Osaka International Cancer Institute ( Site 1161) | Osaka | 541-8567 | Japan | Details | ||
| Oslo Universitetssykehus Radiumhospitalet ( Site 0600) | Oslo | 0379 | Norway | Details | ||
| Ospedale Vito Fazzi ( Site 0547) | Lecce | 73100 | Italy | Details | ||
| Our Lady of the Lake Regional Medical Center. ( Site 0031) | Baton Rouge | Louisiana | 70817 | United States | Details | |
| Parkview Research Center at Parkview Regional Medical Center ( Site 0026) | Fort Wayne | Indiana | 46845 | United States | Details | |
| Peking Union Medical College Hospital ( Site 1001) | Beijing | Beijing | 100730 | China | Details | |
| Peter MacCallum Cancer Centre ( Site 0971) | Melbourne | Victoria | 3000 | Australia | Details | |
| Policlinico Universitario Gemelli ( Site 0538) | Roma | 00168 | Italy | Details | ||
| Princess Margaret Cancer Centre ( Site 0102) | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Ramathibodi Hospital, Mahidol University ( Site 1131) | Rajthevee | Krung Thep Maha Nakhon | 10400 | Thailand | Details | |
| Rambam Medical Center ( Site 0815) | Haifa | 3109601 | Israel | Details | ||
| Royal Brisbane and Women s Hospital ( Site 0972) | Herston | Queensland | 4029 | Australia | Details | |
| Royal Devon and Exeter Foundation Trust Hospital ( Site 0699) | Exeter | England | United Kingdom | Details | ||
| ROYAL MARSDEN HOSPITAL (CHELSEA) ( Site 0701) | London | London, City Of | SW3 6JJ | United Kingdom | Details | |
| Royal Marsden Hospital (Sutton)-Gynaecology Unit ( Site 0696) | London | Surrey | SM3 5PT | United Kingdom | Details | |
| Saitama Cancer Center ( Site 1169) | Kitaadachi-gun | Saitama | 362-0806 | Japan | Details | |
| Saitama Medical University International Medical Center ( Site 1168) | Hidaka | Saitama | 350-1298 | Japan | Details | |
| Samsung Medical Center ( Site 1064) | Seoul | 06351 | Korea, Republic of | Details | ||
| Sanford Bismarck Medical Center ( Site 0046) | Bismarck | North Dakota | 58501 | United States | Details | |
| Sanford Gynecology Oncology ( Site 0003) | Sioux Falls | South Dakota | 57104 | United States | Details | |
| Severance Hospital ( Site 1063) | Seoul | 03722 | Korea, Republic of | Details | ||
| Shanghai Cancer Hospital ( Site 1000) | Shanghai | Shanghai | 200032 | China | Details | |
| Shanghai First Maternity and Infant Hospital-Gynecology department ( Site 1039) | Shanghai | Shanghai | 201204 | China | Details | |
| Sichuan Cancer Hospital ( Site 1018) | Chengdu | Sichuan | 610041 | China | Details | |
| Smilow Cancer Center at Yale-New Haven ( Site 0023) | New Haven | Connecticut | 06510 | United States | Details | |
| Sociedad Oncovida S.A. ( Site 0196) | Santiago | Region M. De Santiago | 7510032 | Chile | Details | |
| Songklanagarind Hospital ( Site 1130) | Hatyai | Songkhla | 90110 | Thailand | Details | |
| Sourasky Medical Center ( Site 0819) | Tel Aviv | 6423906 | Israel | Details | ||
| Srinagarind Hospital. Khon Kaen University ( Site 1132) | Mueang | Khon Kaen | 40002 | Thailand | Details | |
| St James Hospital ( Site 0505) | Dublin | D8 | Ireland | Details | ||
| St John of God Subiaco Hospital ( Site 0969) | Subiaco | Western Australia | 6008 | Australia | Details | |
| Texas Oncology-Austin Central ( Site 8006) | Austin | Texas | 78731 | United States | Details | |
| Texas Oncology-Fort Worth Cancer Center ( Site 8001) | Fort Worth | Texas | 76104 | United States | Details | |
| Texas Oncology-San Antonio Medical Center ( Site 8002) | San Antonio | Texas | 78240 | United States | Details | |
| Texas Oncology-The Woodlands ( Site 8003) | The Woodlands | Texas | 77380 | United States | Details | |
| The First Affiliated Hospital of Xiamen University ( Site 1025) | Xiamen | Fujian | 361003 | China | Details | |
| The First Affiliated Hospital of Xinjiang Medical University ( Site 1012) | Urumqi | Xinjiang | 830054 | China | Details | |
| The First Affiliated Hospital.Sun Yat-sen University ( Site 1005) | Guangzhou | Guangdong | 510080 | China | Details | |
| The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C | Columbus | Ohio | 43210 | United States | Details | |
| UC Davis Comprehensive Cancer Center ( Site 0017) | Sacramento | California | 95817 | United States | Details | |
| UCLA Hematology/Oncology - Westwood (Building 200 Suite 120) ( Site 0027) | Los Angeles | California | 90095 | United States | Details | |
| Universitaetsklinik Leipzig ( Site 0456) | Leipzig | Sachsen | 04103 | Germany | Details | |
| Universitaetsklinikum Carl Gustav Carus der Technischen Univ ( Site 0452) | Dresden | Sachsen | 01307 | Germany | Details | |
| Universitaetsklinikum Freiburg ( Site 0454) | Freiburg | Baden-Wurttemberg | 79106 | Germany | Details | |
| Universitaetsklinikum Hamburg-Eppendorf ( Site 0445) | Hamburg | 20246 | Germany | Details | ||
| University of Colorado Health Sciences Center and Hospital ( Site 0028) | Denver | Colorado | 80262 | United States | Details | |
| University of Kentucky Markey Cancer Center ( Site 0015) | Lexington | Kentucky | 40536 | United States | Details | |
| University of New Mexico Comprehensive Cancer Center-Clinical Research Office ( Site 0019) | Albuquerque | New Mexico | 87106 | United States | Details | |
| University of North Carolina at Chapel Hill ( Site 0025) | Chapel Hill | North Carolina | 27514 | United States | Details | |
| University of the Ryukyus Hospital ( Site 1156) | Nakagami-gun | Okinawa | 903-0215 | Japan | Details | |
| Universitätsmedizin Mannheim-Department of Obstetrics and Gynecology ( Site 0443) | Mannheim | Baden-Wurttemberg | 68167 | Germany | Details | |
| UVA Health System ( Site 0005) | Charlottesville | Virginia | 22908 | United States | Details | |
| UZ Leuven ( Site 0354) | Leuven | Vlaams-Brabant | 3000 | Belgium | Details | |
| UZA University Hospital Antwerp ( Site 0351) | Edegem | Antwerpen | 2650 | Belgium | Details | |
| Virginia Commonwealth University ( Site 0024) | Richmond | Virginia | 23219 | United States | Details | |
| Westmead Hospital ( Site 0973) | Westmead | New South Wales | 2145 | Australia | Details | |
| Willamette Valley Cancer Institute and Research Center ( Site 8000) | Eugene | Oregon | 97401 | United States | Details | |
| Women's Cancer Care ( Site 0039) | Covington | Louisiana | 70433 | United States | Details | |
| Xiangya Hospital Central-South University ( Site 1009) | Changsha | Hunan | 410008 | China | Details | |
| Yaroslavl Regional SBIH Clinical Oncology Hospital ( Site 0734) | Yaroslavl | Yaroslavskaya Oblast | 150054 | Russian Federation | Details | |
| Zhejiang Cancer Hospital ( Site 1004) | Hangzhou | Zhejiang | 310022 | China | Details | |
| Zhejiang Provincial People's Hospital ( Site 1021) | Hangzhou | Zhejiang | 310014 | China | Details |
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