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| NCT ID | NCT04534205 |
| Title | A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1 (AHEAD-MERIT) |
| Acronym | AHEAD-MERIT |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | BioNTech SE |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | SWE | POL | ITA | HUN | GBR | FRA | ESP | DEU | CZE | CAN | BRA | BEL | AUT | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| California Research Institute | RECRUITING | Los Angeles | California | 90027 | United States | Details |
| UCLA Cancer Care | RECRUITING | Los Angeles | California | 90095 | United States | Details |
| Stanford Cancer Institute | COMPLETED | Palo Alto | California | 94304 | United States | Details |
| Yale University | RECRUITING | New Haven | Connecticut | 06511 | United States | Details |
| The George Washington Cancer Center | RECRUITING | Washington | District of Columbia | 20052 | United States | Details |
| University of Miami Miller School of Medicine | RECRUITING | Plantation | Florida | 33324-3274 | United States | Details |
| University of Miami Miller School of Medicine | RECRUITING | Plantation | Florida | 33324 | United States | Details |
| University Cancer and Blood Center | WITHDRAWN | Athens | Georgia | 30607 | United States | Details |
| Winship Cancer Institute | RECRUITING | Atlanta | Georgia | 30322 | United States | Details |
| Norton Cancer Institute | RECRUITING | Louisville | Kentucky | 40241 | United States | Details |
| Tufts Medical Center | RECRUITING | Boston | Massachusetts | 02111 | United States | Details |
| The University of New Mexico Comprehensive Cancer Center | RECRUITING | Albuquerque | New Mexico | 87131 | United States | Details |
| Montefiore Medical Center | RECRUITING | Bronx | New York | 10467 | United States | Details |
| Icahn School of Medicine at Mount Sinai | RECRUITING | New York | New York | 10029 | United States | Details |
| University of Cincinnati Cancer Center | RECRUITING | Cincinnati | Ohio | 45219 | United States | Details |
| Providence Cancer Institute | RECRUITING | Portland | Oregon | 97213 | United States | Details |
| MultiCare Regional Cancer Center | RECRUITING | Tacoma | Washington | 98405 | United States | Details |
| Centro de Oncología e Investigación Buenos Aires COIBA | RECRUITING | Berazategui | B1884BBF | Argentina | Details | |
| Hospital Britanico de Buenos Aires | RECRUITING | Ciudad de Buenos Aires | 1280 | Argentina | Details | |
| Instituto de Oncologia de Cordoba | RECRUITING | Córdoba | X500AA1 | Argentina | Details | |
| Centro Oncologico Riojano Integral | RECRUITING | La Rioja | 5300 | Argentina | Details | |
| Centro de Investigacion Pergamino SA - Clinica Pergamino | RECRUITING | Pergamino | 2700 | Argentina | Details | |
| Instituto de Oncologia de Rosario | RECRUITING | Rosario | 2000 | Argentina | Details | |
| Sanatorio Britanico | RECRUITING | Rosario | 2000 | Argentina | Details | |
| CAIPO Centro para la Atencion Integral del Paciente Oncologico | RECRUITING | San Miguel De Tucumán | 4000 | Argentina | Details | |
| Clinica Viedma | RECRUITING | Viedma | 8500 | Argentina | Details | |
| Cancer Research SA | RECRUITING | Adelaide | 5000 | Australia | Details | |
| Bankstown-Lidcombe Hospital | WITHDRAWN | Bankstown | 2200 | Australia | Details | |
| Flinders Medical Centre | RECRUITING | Bedford Park | 5042 | Australia | Details | |
| Coffs Harbour Hospital | RECRUITING | Coffs Harbour | 2450 | Australia | Details | |
| St Vincent's Hospital | RECRUITING | Fitzroy | VIC 3065 | Australia | Details | |
| Royal North Shore Hospital | RECRUITING | Saint Leonards | 2065 | Australia | Details | |
| John Flynn Private Hospital | RECRUITING | Tugun | 4224 | Australia | Details | |
| Southern Medical Day Care Centre | RECRUITING | Wollongong | 2500 | Australia | Details | |
| LKH - Univ. Klinikum Graz | RECRUITING | Graz | 8036 | Austria | Details | |
| Landeskrankenhaus/ Univ.-Kliniken Innsbruck | RECRUITING | Innsbruck | 6020 | Austria | Details | |
| HNO, Kopf-und Halschirurgie Ordensklinikum Linz Barmherzigen Schwestern | RECRUITING | Linz | 4010 | Austria | Details | |
| Uniklinikum Salzburg, Univ. Klinik fur Innere Medizin III | RECRUITING | Salzburg | 5020 | Austria | Details | |
| Universitair Ziekenhuis Brussel | RECRUITING | Bruxelles | 1090 | Belgium | Details | |
| Universitair Ziekenhuis Gent UZ Gent | RECRUITING | Gent | 9000 | Belgium | Details | |
| CHR de la Citadelle | RECRUITING | Liège | 4000 | Belgium | Details | |
| Fundação PIO XII - Hospital de Amor Barretos | RECRUITING | Barretos | 14784-400 | Brazil | Details | |
| Fundacao Universidade de Caxias do Sul - Instituto de Pesquisas em Saude IPS-UCS | RECRUITING | Caxias Do Sul | 95070-560 | Brazil | Details | |
| Hospital Erasto Gaertner | RECRUITING | Curitiba | 81520-060 | Brazil | Details | |
| Hospial de Caridade de Ijui | RECRUITING | Ijuí | 98700-000 | Brazil | Details | |
| Hospital Marcio Cunha | RECRUITING | Ipatinga | 35162-189 | Brazil | Details | |
| Irmandade Santa Casa de Misericordia de Porto Alegre Hospital Santa Rita | RECRUITING | Porto Alegre | 90050-170 | Brazil | Details | |
| Hospital Mae de Deus | RECRUITING | Porto Alegre | 90110-270 | Brazil | Details | |
| Hospital Sao Lucas da PUCRS | RECRUITING | Porto Alegre | 90610-000 | Brazil | Details | |
| Instituto Nacional de Cancer Jose de Alencar Gomes da Silva - INCA | RECRUITING | Rio De Janeiro | 20231-050 | Brazil | Details | |
| Hospital Sao Rafael | RECRUITING | Salvador | 41253-190 | Brazil | Details | |
| Hospital de Base de Sao Jose do Rio Preto | RECRUITING | São José Do Rio Preto | 15090-000 | Brazil | Details | |
| Instituto do Cancer do Estado de São Paulo | RECRUITING | São Paulo | 01246-000 | Brazil | Details | |
| IBCC - Instituto Brasileiro de Controle do Cancer | RECRUITING | Vila Mariana | 04014-002 | Brazil | Details | |
| Cross Cancer Institute | RECRUITING | Edmonton | T6G 1Z2 | Canada | Details | |
| Jewish General Hospital | RECRUITING | Montreal | H3T 1E2 | Canada | Details | |
| McGill University Health Centre | RECRUITING | Montréal | H4A 3J1 | Canada | Details | |
| Princess Margaret Cancer Centre | RECRUITING | Toronto | M5G 2C1 | Canada | Details | |
| Centro de Estudios Clinicos SAGA | RECRUITING | Santiago | 7500653 | Chile | Details | |
| Fundación Arturo López Pérez | RECRUITING | Santiago | 7500921 | Chile | Details | |
| James Lind Centro de Investigación del Cáncer | RECRUITING | Temuco | 4800827 | Chile | Details | |
| Fakultni Nemocnice Olomouc | RECRUITING | Olomouc | 779 00 | Czechia | Details | |
| Hospital Na Bulovce (Nemocnice na Bulovce) | RECRUITING | Prague 8 - Liben | 180 00 | Czechia | Details | |
| CHU de BORDEAUX, Hopital Saint Andre | RECRUITING | Bordeaux | 33075 | France | Details | |
| Centre Georges Francois Leclerc | RECRUITING | Dijon Cedex | 21079 | France | Details | |
| Clinique Victor Hugo | RECRUITING | Le Mans | 72000 | France | Details | |
| Institut de Radiothérapie Hartmann, GCS CCConcorde | RECRUITING | Levallois-Perret | 92300 | France | Details | |
| Hopital de la Timone | RECRUITING | Marseille | 13005 | France | Details | |
| Hopital Prive du Confluent | RECRUITING | Nantes | 44277 | France | Details | |
| Institut Curie | RECRUITING | Paris | 75005 | France | Details | |
| Institut Curie, Groupe Hospitalier Paris Saint-Joseph (GHPSJ) | RECRUITING | Paris | 75014 | France | Details | |
| CHU de Tours Hopital Bretonneau | RECRUITING | Tours | 37044 | France | Details | |
| Hospital Gustave Roussy | RECRUITING | Villejuif | 94800 | France | Details | |
| Charite Universitätsklinikum Berlin - Campus Benjamin Franklin | RECRUITING | Berlin | 13353 | Germany | Details | |
| Krankenhaus Nordwest GmbH | RECRUITING | Frankfurt am Main | 60488 | Germany | Details | |
| SRH Wald-Klinikum Gera GmbH | WITHDRAWN | Hamburg | 07548 | Germany | Details | |
| Kath. Marien Krankenhaus gGmbH | RECRUITING | Hamburg | 40878 | Germany | Details | |
| Universitaetsklinik Heidelberg | RECRUITING | Heidelberg | 69124 | Germany | Details | |
| Klinik für HNO-Heilkunde, Kopf- und Hals-Chirurgie | RECRUITING | Köln | 50937 | Germany | Details | |
| Universitätsklinikum Leipzig | RECRUITING | Leipzig | 04103 | Germany | Details | |
| Klinikum rechts der Isar der TUM | RECRUITING | München | 81675 | Germany | Details | |
| Univeritätsklinikum Münster | RECRUITING | Münster | 48149 | Germany | Details | |
| Universitaetsmedizin Rostock - Medizinische Klink III (Hamatologie, Onkologie, Palliativmedizin) | RECRUITING | Rostock | 18057 | Germany | Details | |
| Caritas Klinikum Saarbrucken St. Theresia | RECRUITING | Saarbruecken | 66113 | Germany | Details | |
| Medizinische Universitaetsklinik Tuebingen | RECRUITING | Tübingen | 72076 | Germany | Details | |
| Universitaetsklinikum Wuerzburg | RECRUITING | Würzburg | 97080 | Germany | Details | |
| Central Hospital of Northern Pest - Military Hospital | RECRUITING | Budapest | 1062 | Hungary | Details | |
| Uzsoki Utcai Korhaz Onkologiai Osztaly | WITHDRAWN | Budapest | 1145 | Hungary | Details | |
| DEKK Onkologiai Klinika | WITHDRAWN | Debrecen | 4032 | Hungary | Details | |
| Zala Megyei S. Rafael Korhaz | RECRUITING | Zalaegerszeg | 8900 | Hungary | Details | |
| ASST Spedali Civili Brescia | RECRUITING | Brescia | 25123 | Italy | Details | |
| Mater Salutis Hospital AULSS 9 della Regione Veneto | RECRUITING | Legnago | 37045 | Italy | Details | |
| IRCCS Ospedale San Raffaele | RECRUITING | Milano | 20132 | Italy | Details | |
| IRCCS Istituto Europeo di Oncologia | RECRUITING | Milano | 20141 | Italy | Details | |
| Ospedale del Mare | RECRUITING | Napoli | 80147 | Italy | Details | |
| A.O.U. Maggiore della Carita | RECRUITING | Novara | 28100 | Italy | Details | |
| Azienda Ospedaliera Universitaria Senese Policlinico Le Scotte | RECRUITING | Siena | 53100 | Italy | Details | |
| Azienda Sanitaria Universitaria Integrata Friuli Centrale - Presidio ospedaliero di Udine | RECRUITING | Udine | 33100 | Italy | Details | |
| Chungnam National University Hospital | RECRUITING | Daejeon | 35015 | Korea, Republic of | Details | |
| Konyang University Hospital | RECRUITING | Daejeon | 35365 | Korea, Republic of | Details | |
| Chonnam National University Hwasun Hospital | RECRUITING | Hwasun | 58128 | Korea, Republic of | Details | |
| Korea University Anam Hospital | RECRUITING | Seoul | 02841 | Korea, Republic of | Details | |
| Severance Hospital, Yonsei University Health System | RECRUITING | Seoul | 03722 | Korea, Republic of | Details | |
| The Catholic University of Korea, Seoul ST. Mary's Hospital | RECRUITING | Seoul | 06591 | Korea, Republic of | Details | |
| The Catholic University of Korea St. Vincent's Hospital | RECRUITING | Suwon-si | 16247 | Korea, Republic of | Details | |
| Ajou University Hospital | RECRUITING | Suwon-si | 16499 | Korea, Republic of | Details | |
| Centro de Estudios y Prevención del Cáncer (CEPREC) | RECRUITING | Tuxtla Gutiérrez | Region Chiapas | 29038 | Mexico | Details |
| Centro Estatal de Cancerologia de Chihuahua | RECRUITING | Chihuahua | 31000 | Mexico | Details | |
| Cryptex Investigacion SA de CV | RECRUITING | Ciudad De México | 06100 | Mexico | Details | |
| Hospital Civil de Guadalajara Fray Antonio Alcalde | RECRUITING | Guadalajara | 44280 | Mexico | Details | |
| Consultorio del Dr. Joaquín Gabriel Reinoso Toledo | RECRUITING | Monterrey | 64320 | Mexico | Details | |
| Hospital Universitario "Dr Jose Eleuterio Gonzalez" Centro Universitario contra el Cáncer | RECRUITING | Monterrey | 64460 | Mexico | Details | |
| Sociedad de Metabolismo y Corazón S.C. | RECRUITING | Veracruz | 91900 | Mexico | Details | |
| Centro de Atencion e Investigacion Clinica en Oncologia (CAICO) | RECRUITING | Yucatán | 97134 | Mexico | Details | |
| Uniwersyteckie Centrum Kliniczne | RECRUITING | Gdańsk | 80-214 | Poland | Details | |
| Szpitale Pomorskie Sp.zo.o | RECRUITING | Gdynia | 81-519 | Poland | Details | |
| Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie | RECRUITING | Gliwice | 44-102 | Poland | Details | |
| Przychodnia Lekarska KOMED Roman Karaszewski | RECRUITING | Konin | 62-500 | Poland | Details | |
| MCM Pratia Krakow | WITHDRAWN | Kraków | 30-510 | Poland | Details | |
| Centrum Medyczne Pratia Poznań | RECRUITING | Poznań | 60-185 | Poland | Details | |
| Wojskowy Szpital Kliniczny z Poliklinika SP ZOZ | RECRUITING | Wrocław | 50-981 | Poland | Details | |
| Centro Clinico Academico | RECRUITING | Braga | 4710-243 | Portugal | Details | |
| Instituto Português de Oncologia de Coimbra Francisco Gentil, E.P.E. | RECRUITING | Coimbra | 3000-075 | Portugal | Details | |
| Centro Hospitalar de Vila Nova de Gaia/Espinho | RECRUITING | Gaia | 4434-502 | Portugal | Details | |
| Centro Hospitalar Universitario Lisboa Norte | RECRUITING | Lisboa | 1649-028 | Portugal | Details | |
| Instituto Portugues de Oncologia do Porto Francisco Gentil, E.P.E | RECRUITING | Porto | 4200-072 | Portugal | Details | |
| Hospital Clinic Barcelona | RECRUITING | Barcelona | 08036 | Spain | Details | |
| Hospital Univ. Dr. Josep Trueta | RECRUITING | Girona | 17007 | Spain | Details | |
| Complejo Hospitalario de Jaen | RECRUITING | Jaén | 23007 | Spain | Details | |
| Clinica Universidad de Navarra - Madrid (CUN-M) | RECRUITING | Madrid | 28027 | Spain | Details | |
| Hospital Universitario Fundacion Jimenez Diaz | RECRUITING | Madrid | 28040 | Spain | Details | |
| Hospital Universitario La Paz | RECRUITING | Madrid | 28046 | Spain | Details | |
| Hospital Universitario Puerta de Hierro Majadahonda | RECRUITING | Majadahonda | 28222 | Spain | Details | |
| Hospital Regional de Malaga | RECRUITING | Malaga | 29010 | Spain | Details | |
| Hospital Universitario Son Espases | RECRUITING | Palma de Mallorca | 07120 | Spain | Details | |
| Clinica Universidad de Navarra - Pamplona (CUN-P) | RECRUITING | Pamplona | 31008 | Spain | Details | |
| Hospital La Fe | RECRUITING | Valencia | 46026 | Spain | Details | |
| Hospital Miguel Servet | RECRUITING | Zaragoza | 50009 | Spain | Details | |
| Sahlgrenska University Hospital | RECRUITING | Goteborg | 413 45 | Sweden | Details | |
| Skane University Hospital | RECRUITING | Lund | 221 85 | Sweden | Details | |
| Norrlands University Hospital | RECRUITING | Umeå | 901 87 | Sweden | Details | |
| Changhua Christian Hospital | RECRUITING | Changhua | 50006 | Taiwan | Details | |
| Chang Bing Show Chwan Memorial Hospital | RECRUITING | Changhua | 50544 | Taiwan | Details | |
| Kaohsiung Medical University Chung-Ho Memorial Hospital | RECRUITING | Kaohsiung City | 80708 | Taiwan | Details | |
| Chang Gung Memorial Hospital-Kaohsiung Branch | RECRUITING | Kaohsiung | 833401 | Taiwan | Details | |
| Taichung Veterans General Hospital | RECRUITING | Taichung | 407219 | Taiwan | Details | |
| National Taiwan University Hospital | RECRUITING | Taipei | 100225 | Taiwan | Details | |
| Taipei Veterans General Hospital | RECRUITING | Taipei | 11217 | Taiwan | Details | |
| Medical Park Seyhan Hospital | RECRUITING | Adana | 01140 | Turkey | Details | |
| Hacettepe University Cancer Institute | RECRUITING | Ankara | 6230 | Turkey | Details | |
| Trakya University | RECRUITING | Edirne | 22030 | Turkey | Details | |
| Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty | RECRUITING | Istanbul | 34098 | Turkey | Details | |
| Medipol Mega Universite Hastanesi | RECRUITING | Istanbul | 34214 | Turkey | Details | |
| Istanbul Medeniyet University Medical Faculty | RECRUITING | Istanbul | 34722 | Turkey | Details | |
| Ege Universitesi Tip Fakultesi Hastanesi - Tulay Aktas Onkoloji Hastanesi | RECRUITING | İzmir | 35040 | Turkey | Details | |
| Medical Park - Izmir Hastanesi | RECRUITING | İzmir | 35575 | Turkey | Details | |
| Inonu Universitesi - Turgut Ozal Tip Merkezi | RECRUITING | Malatya | 44280 | Turkey | Details | |
| Baskent University | RECRUITING | Yüreğir | 01250 | Turkey | Details | |
| Velindre Cancer Centre | RECRUITING | Cardiff | CF14 2TL | United Kingdom | Details | |
| Beatson West of Scotland Cancer Centre | RECRUITING | Glasgow | G12 0YN | United Kingdom | Details | |
| Leeds Teaching Hospitals NHS Trust (St James's University Hospital) | RECRUITING | Leeds | LS9 7TF | United Kingdom | Details | |
| The Clatterbridge Cancer Centre | RECRUITING | Liverpool | L7 8YA | United Kingdom | Details | |
| Guy's Cancer Centre, Guy's Hospital | RECRUITING | London | SE1 9RT | United Kingdom | Details | |
| The Royal Marsden Hospital NHS Foundation Trust - Fulham Road | RECRUITING | London | SW3 6JJ | United Kingdom | Details | |
| Nottingham University Hospitals NHS Trust | RECRUITING | Nottingham | NG5 1PB | United Kingdom | Details | |
| Oxford Cancer Centre | RECRUITING | Oxford | OX3 7LE | United Kingdom | Details | |
| University Hospital Southampton NHS Foundation Trust | RECRUITING | Southampton | SO16 6YD | United Kingdom | Details | |
| The Royal Marsden Hospital - Sutton | RECRUITING | Sutton | SM2 5PT | United Kingdom | Details |