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| NCT ID | NCT04671667 |
| Title | Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | National Cancer Institute (NCI) |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Alabama at Birmingham Cancer Center | SUSPENDED | Birmingham | Alabama | 35233 | United States | Details |
| University of Arkansas for Medical Sciences | RECRUITING | Little Rock | Arkansas | 72205 | United States | Details |
| Kaiser Permanente-Anaheim | RECRUITING | Anaheim | California | 92806 | United States | Details |
| Kaiser Permanente-Bellflower | RECRUITING | Bellflower | California | 90706 | United States | Details |
| Kaiser Permanente Los Angeles Medical Center | RECRUITING | Los Angeles | California | 90027 | United States | Details |
| Kaiser Permanente-Ontario | RECRUITING | Ontario | California | 91761 | United States | Details |
| Sutter Cancer Centers Radiation Oncology Services-Roseville | ACTIVE_NOT_RECRUITING | Roseville | California | 95661 | United States | Details |
| Sutter Roseville Medical Center | ACTIVE_NOT_RECRUITING | Roseville | California | 95661 | United States | Details |
| Smilow Cancer Center/Yale-New Haven Hospital | RECRUITING | New Haven | Connecticut | 06510 | United States | Details |
| Yale University | RECRUITING | New Haven | Connecticut | 06520 | United States | Details |
| Smilow Cancer Hospital Care Center-Trumbull | RECRUITING | Trumbull | Connecticut | 06611 | United States | Details |
| Smilow Cancer Hospital Care Center - Waterford | RECRUITING | Waterford | Connecticut | 06385 | United States | Details |
| MedStar Washington Hospital Center | RECRUITING | Washington | District of Columbia | 20010 | United States | Details |
| UM Sylvester Comprehensive Cancer Center at Coral Gables | RECRUITING | Coral Gables | Florida | 33146 | United States | Details |
| UM Sylvester Comprehensive Cancer Center at Deerfield Beach | RECRUITING | Deerfield Beach | Florida | 33442 | United States | Details |
| University of Florida Health Science Center - Gainesville | ACTIVE_NOT_RECRUITING | Gainesville | Florida | 32610 | United States | Details |
| University of Miami Miller School of Medicine-Sylvester Cancer Center | RECRUITING | Miami | Florida | 33136 | United States | Details |
| UM Sylvester Comprehensive Cancer Center at Plantation | RECRUITING | Plantation | Florida | 33324 | United States | Details |
| Moffitt Cancer Center-International Plaza | SUSPENDED | Tampa | Florida | 33607 | United States | Details |
| Moffitt Cancer Center - McKinley Campus | RECRUITING | Tampa | Florida | 33612 | United States | Details |
| Moffitt Cancer Center | RECRUITING | Tampa | Florida | 33612 | United States | Details |
| Emory Proton Therapy Center | RECRUITING | Atlanta | Georgia | 30308 | United States | Details |
| Emory University Hospital Midtown | RECRUITING | Atlanta | Georgia | 30308 | United States | Details |
| Emory University Hospital/Winship Cancer Institute | SUSPENDED | Atlanta | Georgia | 30322 | United States | Details |
| Memorial Health University Medical Center | RECRUITING | Savannah | Georgia | 31404 | United States | Details |
| Northwestern University | RECRUITING | Chicago | Illinois | 60611 | United States | Details |
| John H Stroger Jr Hospital of Cook County | RECRUITING | Chicago | Illinois | 60612 | United States | Details |
| University of Illinois | RECRUITING | Chicago | Illinois | 60612 | United States | Details |
| Carle at The Riverfront | RECRUITING | Danville | Illinois | 61832 | United States | Details |
| Cancer Care Specialists of Illinois - Decatur | SUSPENDED | Decatur | Illinois | 62526 | United States | Details |
| Decatur Memorial Hospital | RECRUITING | Decatur | Illinois | 62526 | United States | Details |
| Northwestern Medicine Cancer Center Kishwaukee | RECRUITING | DeKalb | Illinois | 60115 | United States | Details |
| Carle Physician Group-Effingham | RECRUITING | Effingham | Illinois | 62401 | United States | Details |
| Crossroads Cancer Center | RECRUITING | Effingham | Illinois | 62401 | United States | Details |
| Northwestern Medicine Cancer Center Delnor | RECRUITING | Geneva | Illinois | 60134 | United States | Details |
| Northwestern Medicine Lake Forest Hospital | ACTIVE_NOT_RECRUITING | Lake Forest | Illinois | 60045 | United States | Details |
| Carle Physician Group-Mattoon/Charleston | RECRUITING | Mattoon | Illinois | 61938 | United States | Details |
| Loyola University Medical Center | RECRUITING | Maywood | Illinois | 60153 | United States | Details |
| HSHS Saint Elizabeth's Hospital | RECRUITING | O'Fallon | Illinois | 62269 | United States | Details |
| Southern Illinois University School of Medicine | RECRUITING | Springfield | Illinois | 62702 | United States | Details |
| Springfield Clinic | RECRUITING | Springfield | Illinois | 62702 | United States | Details |
| Springfield Memorial Hospital | RECRUITING | Springfield | Illinois | 62781 | United States | Details |
| Carle Cancer Center | RECRUITING | Urbana | Illinois | 61801 | United States | Details |
| The Carle Foundation Hospital | SUSPENDED | Urbana | Illinois | 61801 | United States | Details |
| Northwestern Medicine Cancer Center Warrenville | RECRUITING | Warrenville | Illinois | 60555 | United States | Details |
| Reid Health | RECRUITING | Richmond | Indiana | 47374 | United States | Details |
| Mission Cancer and Blood - Ankeny | RECRUITING | Ankeny | Iowa | 50023 | United States | Details |
| Heartland Oncology and Hematology LLP | RECRUITING | Council Bluffs | Iowa | 51503 | United States | Details |
| Methodist Jennie Edmundson Hospital | RECRUITING | Council Bluffs | Iowa | 51503 | United States | Details |
| Iowa Methodist Medical Center | RECRUITING | Des Moines | Iowa | 50309 | United States | Details |
| Mission Cancer and Blood - Des Moines | RECRUITING | Des Moines | Iowa | 50309 | United States | Details |
| Broadlawns Medical Center | RECRUITING | Des Moines | Iowa | 50314 | United States | Details |
| Iowa Lutheran Hospital | SUSPENDED | Des Moines | Iowa | 50316 | United States | Details |
| Methodist West Hospital | SUSPENDED | West Des Moines | Iowa | 50266-7700 | United States | Details |
| University of Kansas Cancer Center | ACTIVE_NOT_RECRUITING | Kansas City | Kansas | 66160 | United States | Details |
| University of Kansas Cancer Center-Overland Park | ACTIVE_NOT_RECRUITING | Overland Park | Kansas | 66210 | United States | Details |
| University of Kansas Hospital-Indian Creek Campus | ACTIVE_NOT_RECRUITING | Overland Park | Kansas | 66211 | United States | Details |
| University of Kansas Hospital-Westwood Cancer Center | ACTIVE_NOT_RECRUITING | Westwood | Kansas | 66205 | United States | Details |
| University of Kentucky/Markey Cancer Center | ACTIVE_NOT_RECRUITING | Lexington | Kentucky | 40536 | United States | Details |
| The James Graham Brown Cancer Center at University of Louisville | RECRUITING | Louisville | Kentucky | 40202 | United States | Details |
| UofL Health Medical Center Northeast | RECRUITING | Louisville | Kentucky | 40245 | United States | Details |
| Maryland Proton Treatment Center | SUSPENDED | Baltimore | Maryland | 21201 | United States | Details |
| University of Maryland/Greenebaum Cancer Center | RECRUITING | Baltimore | Maryland | 21201 | United States | Details |
| Central Maryland Radiation Oncology in Howard County | RECRUITING | Columbia | Maryland | 21044 | United States | Details |
| UM Baltimore Washington Medical Center/Tate Cancer Center | RECRUITING | Glen Burnie | Maryland | 21061 | United States | Details |
| Tufts Medical Center | RECRUITING | Boston | Massachusetts | 02111 | United States | Details |
| University of Michigan Comprehensive Cancer Center | RECRUITING | Ann Arbor | Michigan | 48109 | United States | Details |
| Wayne State University/Karmanos Cancer Institute | ACTIVE_NOT_RECRUITING | Detroit | Michigan | 48201 | United States | Details |
| Weisberg Cancer Treatment Center | ACTIVE_NOT_RECRUITING | Farmington Hills | Michigan | 48334 | United States | Details |
| Sanford Joe Lueken Cancer Center | RECRUITING | Bemidji | Minnesota | 56601 | United States | Details |
| University of Mississippi Medical Center | RECRUITING | Jackson | Mississippi | 39216 | United States | Details |
| Saint Francis Medical Center | SUSPENDED | Cape Girardeau | Missouri | 63703 | United States | Details |
| Siteman Cancer Center at West County Hospital | ACTIVE_NOT_RECRUITING | Creve Coeur | Missouri | 63141 | United States | Details |
| University of Kansas Cancer Center - North | ACTIVE_NOT_RECRUITING | Kansas City | Missouri | 64154 | United States | Details |
| University of Kansas Cancer Center - Lee's Summit | ACTIVE_NOT_RECRUITING | Lee's Summit | Missouri | 64064 | United States | Details |
| University of Kansas Cancer Center at North Kansas City Hospital | ACTIVE_NOT_RECRUITING | North Kansas City | Missouri | 64116 | United States | Details |
| Washington University School of Medicine | ACTIVE_NOT_RECRUITING | Saint Louis | Missouri | 63110 | United States | Details |
| Siteman Cancer Center-South County | ACTIVE_NOT_RECRUITING | Saint Louis | Missouri | 63129 | United States | Details |
| Siteman Cancer Center at Christian Hospital | ACTIVE_NOT_RECRUITING | Saint Louis | Missouri | 63136 | United States | Details |
| Siteman Cancer Center at Saint Peters Hospital | ACTIVE_NOT_RECRUITING | Saint Peters | Missouri | 63376 | United States | Details |
| Mercy Hospital Springfield | SUSPENDED | Springfield | Missouri | 65804 | United States | Details |
| Benefis Sletten Cancer Institute | RECRUITING | Great Falls | Montana | 59405 | United States | Details |
| Logan Health Medical Center | RECRUITING | Kalispell | Montana | 59901 | United States | Details |
| Community Medical Center | RECRUITING | Missoula | Montana | 59804 | United States | Details |
| Nebraska Cancer Specialists/Oncology Hematology West PC - MECC | RECRUITING | Omaha | Nebraska | 68114 | United States | Details |
| Nebraska Methodist Hospital | RECRUITING | Omaha | Nebraska | 68114 | United States | Details |
| Oncology Associates PC | RECRUITING | Omaha | Nebraska | 68114 | United States | Details |
| University of New Mexico Cancer Center | RECRUITING | Albuquerque | New Mexico | 87106 | United States | Details |
| Mount Sinai Union Square | RECRUITING | New York | New York | 10003 | United States | Details |
| Mount Sinai Chelsea | RECRUITING | New York | New York | 10011 | United States | Details |
| Mount Sinai Hospital | RECRUITING | New York | New York | 10029 | United States | Details |
| Stony Brook University Medical Center | RECRUITING | Stony Brook | New York | 11794 | United States | Details |
| Randolph Hospital | SUSPENDED | Asheboro | North Carolina | 27203 | United States | Details |
| Cone Health Cancer Center | RECRUITING | Greensboro | North Carolina | 27403 | United States | Details |
| Annie Penn Memorial Hospital | RECRUITING | Reidsville | North Carolina | 27320 | United States | Details |
| Sanford Bismarck Medical Center | RECRUITING | Bismarck | North Dakota | 58501 | United States | Details |
| Sanford Roger Maris Cancer Center | RECRUITING | Fargo | North Dakota | 58122 | United States | Details |
| Indu and Raj Soin Medical Center | RECRUITING | Beavercreek | Ohio | 45431 | United States | Details |
| Dayton Physicians LLC-Miami Valley South | RECRUITING | Centerville | Ohio | 45459 | United States | Details |
| Miami Valley Hospital South | RECRUITING | Centerville | Ohio | 45459 | United States | Details |
| Cleveland Clinic Foundation | RECRUITING | Cleveland | Ohio | 44195 | United States | Details |
| Premier Blood and Cancer Center | RECRUITING | Dayton | Ohio | 45409 | United States | Details |
| Dayton Physician LLC - Englewood | RECRUITING | Dayton | Ohio | 45415 | United States | Details |
| Miami Valley Hospital North | RECRUITING | Dayton | Ohio | 45415 | United States | Details |
| Atrium Medical Center-Middletown Regional Hospital | RECRUITING | Franklin | Ohio | 45005-1066 | United States | Details |
| Dayton Physicians LLC-Atrium | RECRUITING | Franklin | Ohio | 45005 | United States | Details |
| Miami Valley Cancer Care and Infusion | RECRUITING | Greenville | Ohio | 45331 | United States | Details |
| Greater Dayton Cancer Center | RECRUITING | Kettering | Ohio | 45409 | United States | Details |
| Kettering Medical Center | RECRUITING | Kettering | Ohio | 45429 | United States | Details |
| Upper Valley Medical Center | RECRUITING | Troy | Ohio | 45373 | United States | Details |
| Cancer Centers of Southwest Oklahoma Research | RECRUITING | Lawton | Oklahoma | 73505 | United States | Details |
| University of Oklahoma Health Sciences Center | RECRUITING | Oklahoma City | Oklahoma | 73104 | United States | Details |
| Clackamas Radiation Oncology Center | SUSPENDED | Clackamas | Oregon | 97015 | United States | Details |
| Providence Cancer Institute Clackamas Clinic | RECRUITING | Clackamas | Oregon | 97015 | United States | Details |
| Providence Newberg Medical Center | RECRUITING | Newberg | Oregon | 97132 | United States | Details |
| Providence Portland Medical Center | RECRUITING | Portland | Oregon | 97213 | United States | Details |
| Providence Saint Vincent Medical Center | RECRUITING | Portland | Oregon | 97225 | United States | Details |
| UPMC Altoona | RECRUITING | Altoona | Pennsylvania | 16601 | United States | Details |
| Geisinger Medical Center | RECRUITING | Danville | Pennsylvania | 17822 | United States | Details |
| Geisinger Medical Oncology-Lewisburg | RECRUITING | Lewisburg | Pennsylvania | 17837 | United States | Details |
| Thomas Jefferson University Hospital | RECRUITING | Philadelphia | Pennsylvania | 19107 | United States | Details |
| Fox Chase Cancer Center | RECRUITING | Philadelphia | Pennsylvania | 19111 | United States | Details |
| Jefferson Torresdale Hospital | RECRUITING | Philadelphia | Pennsylvania | 19114 | United States | Details |
| Temple University Hospital | ACTIVE_NOT_RECRUITING | Philadelphia | Pennsylvania | 19140 | United States | Details |
| University of Pittsburgh Cancer Institute (UPCI) | RECRUITING | Pittsburgh | Pennsylvania | 15232 | United States | Details |
| UPMC-Shadyside Hospital | ACTIVE_NOT_RECRUITING | Pittsburgh | Pennsylvania | 15232 | United States | Details |
| UPMC-Passavant Hospital | RECRUITING | Pittsburgh | Pennsylvania | 15237 | United States | Details |
| Geisinger Wyoming Valley/Henry Cancer Center | RECRUITING | Wilkes-Barre | Pennsylvania | 18711 | United States | Details |
| UPMC Memorial | RECRUITING | York | Pennsylvania | 17408 | United States | Details |
| Medical University of South Carolina | RECRUITING | Charleston | South Carolina | 29425 | United States | Details |
| Avera Cancer Institute | RECRUITING | Sioux Falls | South Dakota | 57105 | United States | Details |
| Sanford USD Medical Center - Sioux Falls | RECRUITING | Sioux Falls | South Dakota | 57117-5134 | United States | Details |
| Avera Cancer Institute at Yankton | RECRUITING | Yankton | South Dakota | 57078 | United States | Details |
| Vanderbilt University/Ingram Cancer Center | RECRUITING | Nashville | Tennessee | 37232 | United States | Details |
| Huntsman Cancer Institute/University of Utah | ACTIVE_NOT_RECRUITING | Salt Lake City | Utah | 84112 | United States | Details |
| VCU Massey Cancer Center at Stony Point | RECRUITING | Richmond | Virginia | 23235 | United States | Details |
| Virginia Commonwealth University/Massey Cancer Center | RECRUITING | Richmond | Virginia | 23298 | United States | Details |
| ThedaCare Regional Cancer Center | RECRUITING | Appleton | Wisconsin | 54911 | United States | Details |
| HSHS Sacred Heart Hospital | RECRUITING | Eau Claire | Wisconsin | 54701 | United States | Details |
| Saint Vincent Hospital Cancer Center Green Bay | RECRUITING | Green Bay | Wisconsin | 54301 | United States | Details |
| Saint Vincent Hospital Cancer Center at Saint Mary's | RECRUITING | Green Bay | Wisconsin | 54303 | United States | Details |
| Froedtert Menomonee Falls Hospital | RECRUITING | Menomonee Falls | Wisconsin | 53051 | United States | Details |
| Medical College of Wisconsin | RECRUITING | Milwaukee | Wisconsin | 53226 | United States | Details |
| Drexel Town Square Health Center | SUSPENDED | Oak Creek | Wisconsin | 53154 | United States | Details |
| Saint Vincent Hospital Cancer Center at Sturgeon Bay | RECRUITING | Sturgeon Bay | Wisconsin | 54235-1495 | United States | Details |
| Froedtert West Bend Hospital/Kraemer Cancer Center | RECRUITING | West Bend | Wisconsin | 53095 | United States | Details |