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NCT ID	NCT05152147
Title	A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers (HERIZON-GEA-01)
Acronym	HERIZON-GEA-01
Recruitment	Recruiting
Gender	both
Phase	Phase III
Variant Requirements	No
Sponsors	Zymeworks Inc.
Indications	gastroesophageal adenocarcinoma gastric adenocarcinoma esophagus adenocarcinoma gastroesophageal junction adenocarcinoma
Therapies	Capecitabine + Oxaliplatin + Trastuzumab Capecitabine + Oxaliplatin + ZW25 Cisplatin + Fluorouracil + Trastuzumab Cisplatin + Fluorouracil + ZW25 Cisplatin + Fluorouracil + Tislelizumab + ZW25 Capecitabine + Oxaliplatin + Tislelizumab + ZW25
Age Groups:	adult \| senior
Covered Countries	TUR \| ROU \| POL \| NLD \| ITA \| IRL \| GRC \| GBR \| FRA \| EST \| ESP \| DEU \| CZE \| CAN \| BRA \| BEL \| AUS \| ARG