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| NCT ID | NCT05152147 |
| Title | A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers (HERIZON-GEA-01) |
| Acronym | HERIZON-GEA-01 |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Jazz Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | TUR | ROU | POL | NLD | ITA | IRL | GRC | GBR | FRA | EST | ESP | DEU | CAN | BRA | BEL | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Hospital de Gastroenterología Dr Bonorino Udaondo | Buenos Aires | 1264 | Argentina | Details | ||
| Hospital Italiano de Buenos Aires | Buenos Aires | C1181ACH | Argentina | Details | ||
| Instituto de Investigaciones Metabólicas - IDIM | Ciudad Autónoma de Buenos Aires | C1012 | Argentina | Details | ||
| Fundación Centro de Medicina Nuclear y Molecular ER | Córdoba | X5000HXL | Argentina | Details | ||
| Centro Médico Privado CEMAIC | Córdoba | X5008HHW | Argentina | Details | ||
| Centro de Investigación Pergamino S.A. | Pergamino | 2700 | Argentina | Details | ||
| Centro de Investigación Clínica - Clínica Viedma | Viedma | R8500ACE | Argentina | Details | ||
| Flinders Medical Centre | Bedford Park | 5042 | Australia | Details | ||
| Austin Health | Heidelberg | 3084 | Australia | Details | ||
| Liverpool Hospital | Liverpool | 2170 | Australia | Details | ||
| Fiona Stanley Hospital | Murdoch | 6150 | Australia | Details | ||
| Imelda VZW | Bonheiden | 2820 | Belgium | Details | ||
| Cliniques Universitaires Saint-Luc | Brussels | 1200 | Belgium | Details | ||
| UZ Gent | Gent | 9000 | Belgium | Details | ||
| UZ Leuven | Leuven | 3000 | Belgium | Details | ||
| CHU de Liège | Liège | 4000 | Belgium | Details | ||
| Centro Integrado de Pesquisa - CIP | Barretos | 14784-400 | Brazil | Details | ||
| Fundação Pio XII Hospital de Câncer de Barretos | Barretos | 14784-400 | Brazil | Details | ||
| Cenantron - Centro Avancado de Tratamento Oncologico Ltda | Belo Horizonte | 30130-090 | Brazil | Details | ||
| Centro de Pesquisas Clínicas/Fundação Doutor Amaral Carvalho | Brasília | 70840-901 | Brazil | Details | ||
| Instituto Do Câncer Do Ceará ICC | Fortaleza | 60430-230 | Brazil | Details | ||
| Hospital de Clinicas de Porto Alegre (HCPA) - PPDS | Porto Alegre | 90050-170 | Brazil | Details | ||
| Irmandade Da Santa Casa de Misericordia de Porto Alegre | Porto Alegre | 90050-170 | Brazil | Details | ||
| Hospital Nossa Senhora Da Conceição | Porto Alegre | 91350-200 | Brazil | Details | ||
| Núcleo de Pesquisa Clínica da Rede São Camilo | Santo André | 09060-650 | Brazil | Details | ||
| Instituto de Oncologia de Sorocaba | Sorocaba | 18030-075 | Brazil | Details | ||
| Instituto do Cancer do Estado de São Paulo ICESP | São Paulo | 01246-000 | Brazil | Details | ||
| Princess Margaret Cancer Centre | Toronto | M5G 2C1 | Canada | Details | ||
| Centro Internacional de Estudios Clinicos CIEC | Santiago | Region Metropolitan | 8420383 | Chile | Details | |
| Fundación Arturo López Pérez (FALP) - PPDS | Providencia | Región-Metropolitana De Santiago | 7500000 | Chile | Details | |
| Centro de Estudios Clínicos SAGA SpA | Providencia | 7500000 | Chile | Details | ||
| Sociedad Oncovida S.A | Santiago | 7500000 | Chile | Details | ||
| Icegclinic | Santiago | 8150513 | Chile | Details | ||
| BIOCINETIC SpA | Santiago | 8330336 | Chile | Details | ||
| Sociedad de Investigaciones Medicas Limitada | Temuco | 4810469 | Chile | Details | ||
| Beijing Chao-Yang Hospital, Capital Medical University | Beijing | 100020 | China | Details | ||
| Cancer Hospital Chinese Academy of Medical Sciences | Beijing | 100021 | China | Details | ||
| Beijing Cancer Hospital | Beijing | 100142 | China | Details | ||
| Peking University Third Hospital | Beijing | 100191 | China | Details | ||
| Beijing Luhe Hospital, Capital Medical University | Beijing | 101199 | China | Details | ||
| The First Affiliated Hospital of Bengbu Medical College | Bengbu | 233004 | China | Details | ||
| Hunan Cancer Hospital | Changsha | 410031 | China | Details | ||
| Changzhi People's Hospital | Changzhi | 046099 | China | Details | ||
| Changzhou First People's Hospital | Changzhou | 213004 | China | Details | ||
| Sichuan Cancer Hospital & Institute | Chengdu | 610042 | China | Details | ||
| The First Affiliated Hospital of Fujian Medical University | Fuzhou | 350005 | China | Details | ||
| Fujian Cancer Hospital | Fuzhou | 350014 | China | Details | ||
| Guangdong Provincial People's Hospital | Guangzhou | 510055 | China | Details | ||
| The Sixth Affiliated Hospital of Sun Yat-sen University | Guangzhou | 510655 | China | Details | ||
| Hainan General Hospital | Haikou | 570311 | China | Details | ||
| The First Affiliated Hospital, College of Medicine, Zhejiang University | Hangzhou | 310003 | China | Details | ||
| Sir Run Run Shaw Hospital, Zhejiang University School of Medicine | Hangzhou | 310016 | China | Details | ||
| Second Affiliated Hospital of Zhejiang University School of Medicine | Hangzhou | 310017 | China | Details | ||
| Zhejiang Cancer Hospital | Hangzhou | 310022 | China | Details | ||
| Harbin Medical University Cancer Hospital | Harbin | 150081 | China | Details | ||
| Anhui Provincial Cancer Hospital | Hefei | 230031 | China | Details | ||
| The Second Affiliated Hospital of Anhui Medical University | Hefei | 230601 | China | Details | ||
| Affiliated Hospital of Inner Mongolia Medical University | Hohhot | 01000 | China | Details | ||
| Shandong Cancer Hospital | Jinan | 250000 | China | Details | ||
| Jinan Central Hospital | Jinan | 250013 | China | Details | ||
| Yunnan Cancer Hospital | Kunming | 650118 | China | Details | ||
| The First Hospital of Lanzhou University | Lanzhou | 730013 | China | Details | ||
| Gansu Cancer Hospital | Lanzhou | 730050 | China | Details | ||
| The First Affiliated Hospital of Nanchang University | Nanchang | 330052 | China | Details | ||
| Nanjing Drum Tower Hospital ,The Affiliated Hospital of Nanjing University Medical School | Nanjing | 210008 | China | Details | ||
| The Affiliated Hospital of Qingdao University | Qingdao | 266003 | China | Details | ||
| Ruijin hospital Shanghai Jiao Tong University School of Medicine | Shanghai | 200025 | China | Details | ||
| Fudan University Affiliated Zhongshan Hospital | Shanghai | 200032 | China | Details | ||
| Fudan University Shanghai Cancer Center | Shanghai | 200032 | China | Details | ||
| Shanghai General Hospital | Shanghai | 200080 | China | Details | ||
| Liaoning Cancer Hospital & Institute | Shenyang | 110801 | China | Details | ||
| The Fourth Hospital of Hebei Medical University | Shijiazhuang | 50011 | China | Details | ||
| Tianjin Medical University General Hospital | Tianjin | 300041 | China | Details | ||
| Tianjin Medical University Cancer Institute & Hospital | Tianjin | 300060 | China | Details | ||
| The Tonghua Central Hospital | Tonghua | 143099 | China | Details | ||
| Weihai Municipal Hospital | Weihai | 264200 | China | Details | ||
| The First Affiliated Hospital of Wenzhou Medical University | Wenzhou | 325000 | China | Details | ||
| Union Hospital Tongji Medical College HuaZhong University of Science and Technology | Wuhan | 430023 | China | Details | ||
| Hubei Cancer Hospital | Wuhan | 430079 | China | Details | ||
| Affiliated Hospital of Jiangnan University | Wuxi | 214062 | China | Details | ||
| First Affiliated Hospital of Xi 'an Jiaotong University | Xi'an | 710061 | China | Details | ||
| The First Affiliated Hospital of Xiamen University | Xiamen | 361003 | China | Details | ||
| Northern Jiangsu People's Hospital | Yangzhou | 225001 | China | Details | ||
| Henan Cancer Hospital | Zhengzhou | 450003 | China | Details | ||
| The First Affiliated Hospital of Zhengzhou University | Zhengzhou | 450052 | China | Details | ||
| Cancer Hospital affiliated to Xinjiang Medical University | Ürümqi | 830026 | China | Details | ||
| North Estonia Medical Centre Foundation | Tallinn | 13419 | Estonia | Details | ||
| CHU de Bordeaux - Hopital Haut Leveque | Pessac | Gironde | 33600 | France | Details | |
| Sainte-Catherine, Institut du Cancer Avignon Provence | Avignon | 84000 | France | Details | ||
| EDOG - Institut Bergonie - PPDS | Bordeaux | 33000 | France | Details | ||
| Universite de Bourgogne - Faculte de Medecine - IN | Dijon | 21079 | France | Details | ||
| Centre Hospitalier Universitaire Grenoble Alpes - Hopital Albert Michallon | Grenoble | 38043 | France | Details | ||
| Centre Léon Berard | Lyon | 69008 | France | Details | ||
| EDOG Institut de Cancerologie de l'Ouest - PPDS | Nantes | 44805 | France | Details | ||
| CHRU de Poitiers La Miletrie | Poitiers | 86021 | France | Details | ||
| EDOG - Centre Eugene Marquis Centre Regional de Lutte Contre Le Cancer - PPDS | Rennes | 35000 | France | Details | ||
| CHRU de Brest - Hopital Morvan | Saint-Priest-en-Jarez | 42270 | France | Details | ||
| Hôpital de Rangueil | Toulouse | 69437 | France | Details | ||
| Hôpital Saint Antoine | Villejuif | 94800 | France | Details | ||
| Research Institute of Clinical Medicine | Tbilisi | 0112 | Georgia | Details | ||
| High Technology Hospital MedCenter Ltd | Tbilisi | 6000 | Georgia | Details | ||
| Institut für Klinisch-Onkologische Forschung | Frankfurt am Main | Hessen | 60488 | Germany | Details | |
| Attikon University General Hospital | Athens | 124 64 | Greece | Details | ||
| Bioclinic Thessaloniki Oncology Department | Thessaloniki | 54622 | Greece | Details | ||
| Agios Loucas Clinic SA | Thessaloniki | 552 36 | Greece | Details | ||
| Interbalkan Medical Center of Thessaloniki Oncology Department | Thessaloniki | 57001 | Greece | Details | ||
| Clinica Medica Especializada CELAN | Guatemala City | 01010 | Guatemala | Details | ||
| Grupo Medico Angeles | Guatemala City | 01015 | Guatemala | Details | ||
| Centro Medico Integral de Cancerologia CEMIC | Salcaja | 09002 | Guatemala | Details | ||
| All India Institute of Medical Sciences, Bhubaneswar | Bhubaneswar | 751019 | India | Details | ||
| Artemis Hospital | Gurgaon | 122003 | India | Details | ||
| MNJ Institute of Oncology and Regional Cancer Centre | Hyderabad | 500004 | India | Details | ||
| Indraprastha Apollo Hospitals | New Delhi | 110076 | India | Details | ||
| Regional Cancer Centre Indira Gandhi Institute of Medical Sciences | Patna | 800014 | India | Details | ||
| HCG City Cancer Center | Vijayawada | 520002 | India | Details | ||
| St James's Hospital | Dublin | 8 | Ireland | Details | ||
| Azienda Ospedaliero Universitaria Di Bologna - Policlinico S Orsola Malpighi | Bologna | 40138 | Italy | Details | ||
| Fondazione del Piemonte per l'Oncologia (IRCCS) | Candiolo | 10060 | Italy | Details | ||
| Ospedale Policlinico San Martino | Genova | 16132 | Italy | Details | ||
| Istituto Scientifico Romagnolo Per Lo Studio E La Cura Dei Tumori IRST - PPDS | Meldola | 47014 | Italy | Details | ||
| Ospedale San Raffaele S.r.l. - PPDS | Milano | 20132 | Italy | Details | ||
| Istituto Nazionale Dei Tumori | Milano | 20133 | Italy | Details | ||
| ASST Grande Ospedale Metropolitano Niguarda - Presidio Ospedaliero Ospedale Niguarda | Milano | 20162 | Italy | Details | ||
| Azienda Ospedaliero Universitaria Di Modena Policlinico | Modena | 41124 | Italy | Details | ||
| Arcispedale Santa Maria Nuova | Reggio Emilia | 43100 | Italy | Details | ||
| Fondazione Policlinico Universitario A Gemelli | Rome | 00168 | Italy | Details | ||
| Centro Ricerche Cliniche Di Verona | Verona | 37134 | Italy | Details | ||
| Azienda ULSS 8 "Berica" - Ospedale San Bortolo | Vicenza | 36100 | Italy | Details | ||
| Gifu University Hospital | Gifu-Shi | Gihu | 501-1112 | Japan | Details | |
| Gunma Prefectural Cancer Center | Ota-shi | Gunma | 373-8550 | Japan | Details | |
| Hyogo Cancer Center | Akashi-shi | Hyôgo | 673-8558 | Japan | Details | |
| Ibaraki Prefectural Central Hospital | Kasama-Shi | Ibaraki | 309-1793 | Japan | Details | |
| Kagawa University Hospital | Kita-Gun Miki-Cho | Kagawa | 761-0701 | Japan | Details | |
| Kanagawa Cancer Center | Yokohama-Shi Asahi-Ku | Kanagawa | 241-0815 | Japan | Details | |
| Kumamoto University Hospital - Honjo-Kuhonji Campus A | Chuo-Ku | Kumamoto | 860-8556 | Japan | Details | |
| Kyoto University Hospital | Sakyo-ku | Kyoto-shi | 606-8507 | Japan | Details | |
| Osaki Citizen Hospital | Osaki-Shi | Miyagi | 989-6136 | Japan | Details | |
| Kurashiki Central Hospital | Kurashiki-Shi | Okayama | 710-0052 | Japan | Details | |
| Osaka University Hospital | Suita-Shi | Osaka | 565-0871 | Japan | Details | |
| Osaka Medical and Pharmaceutical University Hospital | Takatsuki-Shi | Osaka | 569-8686 | Japan | Details | |
| Chiba Cancer Center | Chiba-Shi | Tiba | 260-0801 | Japan | Details | |
| National Cancer Center Hospital East | Kashiwa-shi | Tiba | 277-8577 | Japan | Details | |
| Keio University Hospital | Shinjuku-Ku | Tokyo | 160-8582 | Japan | Details | |
| National Cancer Center Hospital | Chuo Ku | 104-0045 | Japan | Details | ||
| National Hospital Organization Kyushu Cancer Center | Fukuoka-shi | 811-1395 | Japan | Details | ||
| Saitama Cancer Center | Ina | 362-0806 | Japan | Details | ||
| Shikoku Cancer Center | Matsuyama | 791-0245 | Japan | Details | ||
| Kindai University Hospital | Osaka-sayama | 589-0014 | Japan | Details | ||
| Osaka International Cancer Institute | Osaka | 540-0008 | Japan | Details | ||
| The Cancer Institute Hospital of Japanese Foundation For Cancer Research | Tokyo | 135-8550 | Japan | Details | ||
| Hallym University Sacred Heart Hospital | Anyang-si | 14068 | Korea, Republic of | Details | ||
| Dong-A University Hospital | Busan | 49201 | Korea, Republic of | Details | ||
| Kyungpook National University Chilgok Hospital | Daegu | 41404 | Korea, Republic of | Details | ||
| National Cancer Center | Goyang-si | 10408 | Korea, Republic of | Details | ||
| Gachon University Gil Medical Center | Incheon | 21565 | Korea, Republic of | Details | ||
| CHA Bundang Medical Center, CHA University | Seongnam-si | 13496 | Korea, Republic of | Details | ||
| Seoul National University Bundang Hospital | Seongnam-si | 13620 | Korea, Republic of | Details | ||
| Korea University Anam Hospital | Seoul | 02841 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| The Catholic University of Korea, Seoul St. Mary's Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Kangbuk Samsung Hospital | Seoul | 03181 | Korea, Republic of | Details | ||
| Severance Hospital Yonsei University Health System - PPDS | Seoul | 03686 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Gangnam Severance Hospital, Yonsei University Health System | Seoul | 06229 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Korea University Guro Hospital | Seoul | 08308 | Korea, Republic of | Details | ||
| Hospital Pulau Pinang | George Town | 10990 | Malaysia | Details | ||
| Sarawak General Hospital | Kuching | 93586 | Malaysia | Details | ||
| National Cancer Institute ( Institut Kanser Negara) | Putrajaya | 62675 | Malaysia | Details | ||
| Health Pharma Professional Research S.A de C.V. | Mexico City | 03100 | Mexico | Details | ||
| Hospital Universitario Dr. Jose Eleuterio González | Monterrey | 64460 | Mexico | Details | ||
| Centro de Investigacion Clinica de Oaxaca | Oaxaca | 68020 | Mexico | Details | ||
| Catharina Hospital | Eindhoven | 5623 EJ | Netherlands | Details | ||
| Leids Universitair Medisch Centrum | Leiden | 2333 ZA | Netherlands | Details | ||
| ETZ-Elisabeth | Tilburg | 5042 AD | Netherlands | Details | ||
| Centrum Onkologii Instytut im. Marii Sklodowskiej-Curie | Warszawa | 02-034 | Poland | Details | ||
| Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Lodzi | Łódź | 93-513 | Poland | Details | ||
| Hospital Garcia de Orta | Almada | 2801-951 | Portugal | Details | ||
| Centro Hospitalar E Universitário de Coimbra EPE | Coimbra | 3000-459 | Portugal | Details | ||
| Hospital Senhora da Oliveira - Guimaraes, E.P.E | Guimarães | 4830-044 | Portugal | Details | ||
| Centro Hospitalar Lisboa Norte, E.P.E. - Hospital de Santa Maria | Lisboa | 1649-035 | Portugal | Details | ||
| Unidade Local de Saúde de Matosinhos SA | Matosinhos | 4454-509 | Portugal | Details | ||
| Centro Hospitalar do Porto EPE | Porto | 4099-001 | Portugal | Details | ||
| Instituto Portugues de Oncologia Do Porto Francisco Gentil Epe - PPDS | Porto | 4200-072 | Portugal | Details | ||
| Fundeni Clinical Institute | București | 022328 | Romania | Details | ||
| Prof Dr I Chiricuta Institute of Oncology - PPDS | Cluj-Napoca | 400015 | Romania | Details | ||
| Medisprof SRL | Cluj-Napoca | 400641 | Romania | Details | ||
| Oncology Center Sfantul Nectarie | Craiova | 200347 | Romania | Details | ||
| University Clinical Center of Serbia - PPDS | Belgrade | 11000 | Serbia | Details | ||
| Clinical Hospital Center Bezanijska Kosa | Belgrade | 11070 | Serbia | Details | ||
| University Clinical Center Nis | Niš | 18000 | Serbia | Details | ||
| Oncology Institute of Vojvodina | Sremska Kamenica | 21204 | Serbia | Details | ||
| National Cancer Center Singapore | Singapore | 258500 | Singapore | Details | ||
| Wilgers Oncology Centre | Pretoria | 0184 | South Africa | Details | ||
| Corporacio Sanitaria Parc Tauli | Sabadell | Barcelona | 08208 | Spain | Details | |
| Complejo Hospitalario de Navarra | Pamplona | Navarra | 31008 | Spain | Details | |
| Hospital Universitario Germans Trias i Pujol | Badalona | 8915 | Spain | Details | ||
| Hospital Universitario Vall d'Hebron - PPDS | Barcelona | 08035 | Spain | Details | ||
| Hospital Universitari de Girona Dr Josep Trueta | Girona | 17007 | Spain | Details | ||
| Institut Català d'Oncologia (Hospital Duran y Reynals) | L'Hospitalet de Llobregat | 08908 | Spain | Details | ||
| Hospital Universitario Ramon y Cajal | Madrid | 28034 | Spain | Details | ||
| Hospital Universitario La Paz - PPDS | Madrid | 28046 | Spain | Details | ||
| Hospital Regional Universitario de Malaga - Hospital General | Málaga | 29010 | Spain | Details | ||
| Complejo Asistencial Universitario de Salamanca - H. Clinico | Salamanca | 32911 | Spain | Details | ||
| Hospital Universitario Marques de Valdecilla | Santander | 39008 | Spain | Details | ||
| Hospital Universitario Virgen Macarena | Sevilla | 41009 | Spain | Details | ||
| Hospital Universitario Miguel Servet | Zaragoza | 50009 | Spain | Details | ||
| China Medical University Hospital | Taichung | 404472 | Taiwan | Details | ||
| Taipei Veterans General Hospital | Taipei | 11217 | Taiwan | Details | ||
| Phramongkutklao Hospital | Bangkok | 10400 | Thailand | Details | ||
| Songklanagarind Hospital | Hat Yai | 90110 | Thailand | Details | ||
| Srinagarind Hospital, Khon Kaen University | Khon Kaen | 40000 | Thailand | Details | ||
| Hacettepe Universitesi Kanser Enstitusu | Ankara | 06230 | Turkey | Details | ||
| Trakya University Medical Faculty | Edirne | 22030 | Turkey | Details | ||
| Dokuz Eylul Universitesi | Izmir | 35220 | Turkey | Details | ||
| Acibadem Adana Hospital | Seyhan | 01130 | Turkey | Details | ||
| Medical Park Trabzon Yildizli | Trabzon | 61310 | Turkey | Details | ||
| Dr. Abdurrahman Yurtaslan Ankara Onkology Training and Research Hospital | Yenimahalle | 06200 | Turkey | Details | ||
| The Municipal Enterprise Volyn Regional Medical Oncology Centre of the Volyn Regional Council | Lutsk | 43018 | Ukraine | Details | ||
| Bristol Haematology and Oncology Centre | Bristol | BS2 8ED | United Kingdom | Details | ||
| Western General Hospital Edinburgh - PPDS | Edinburgh | EH4 2XU | United Kingdom | Details | ||
| St James University Hospital | Leeds | LS9 7TF | United Kingdom | Details | ||
| Guy's and St Thomas' NHS Foundation Trust - Guy's Hospital | London | SE1 9RT | United Kingdom | Details | ||
| Royal Marsden Hospital - London | London | SW7 3RP | United Kingdom | Details | ||
| Royal Marsden Hospital - Surrey | London | SW7 3RP | United Kingdom | Details | ||
| Edith Cavell Hospital | Peterborough | PE3 9GZ | United Kingdom | Details | ||
| Weston Park Cancer Centre | Sheffield | S10 2SJ | United Kingdom | Details |