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| NCT ID | NCT05386550 |
| Title | Phase III Xevinapant (Debio 1143) and Radiotherapy in Resected LA SCCHN, High Risk, Cisplatin-ineligible Participants (XRAY VISION) |
| Recruitment | Terminated |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | EMD Serono Research & Development Institute, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ROU | POL | NLD | ITA | ISR | GRC | GBR | FRA | ESP | DEU | CZE | CHE | CAN | BRA | BEL | AUT | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Alabama at Birmingham - Dept of Radiation Oncology | Birmingham | Alabama | 35249 | United States | Details | |
| The University of Arizona Cancer Center | Tucson | Arizona | 85719 | United States | Details | |
| UC Health | Aurora | Colorado | 80045 | United States | Details | |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201 | United States | Details | |
| Montefiore Medical Center Radiology | Bronx | New York | 10461 | United States | Details | |
| Perlmutter Cancer Center at NYU Langone Hospital ae Long Island | New York | New York | 10016 | United States | Details | |
| University of Cincinnati Cancer Institute | Cincinnati | Ohio | 45219 | United States | Details | |
| University of Pittsburgh Medical Center Health System - UPMC Department of Dermatology | Pittsburgh | Pennsylvania | 15219 | United States | Details | |
| Prisma Health Cancer Institute, ITOR, CRU | Greenville | South Carolina | 29605 | United States | Details | |
| Instituto de Oncologia Angel Roffo | Ciudad Autonoma Buenos Aires | Argentina | Details | |||
| Centro Oncologico Riojano Integral (CORI) | La Rioja | Argentina | Details | |||
| CEMAIC- Centro Medico Privado | Las Margaritas | Argentina | Details | |||
| Fundacion Scherbovsky | Mendoza | Argentina | Details | |||
| Clinica Viedma S.A. | Viedma | Argentina | Details | |||
| Universitatsklinikum Graz | Graz | Austria | Details | |||
| Krankenhaus der barmherzigen Schwestern Linz - Abteilung für HNO | Linz | Austria | Details | |||
| LKH - Universitätsklinikum der PMU Salzburg - Innere Med III/Hämatologie und Onkologie | Salzburg | Austria | Details | |||
| Institut Jules Bordet - Medical Oncology | Anderlecht | Belgium | Details | |||
| Cliniques Universitaires Saint-Luc - STL | Bruxelles | Belgium | Details | |||
| Antwerp University Hospital (UZA Parent) | Edegem | Belgium | Details | |||
| Vitaz | Sint-Niklaas | Belgium | Details | |||
| Hospital de Câncer de Barretos - Fundação Pio XII - Hospital de Amor | Barretos | Brazil | Details | |||
| Hospital Erasto Gaertner - Liga Paranaense de Combate ao Câncer | Curitiba | Brazil | Details | |||
| CEPON - Centro de Pesquisas Oncológicas de Santa Catarina - Pesquisa Clínica | Florianópolis | Brazil | Details | |||
| CRIO - Centro Regional Integrado de Oncologia | Fortaleza | Brazil | Details | |||
| Oncosite - Centro de Pesquisa Clinica e Oncologia | Ijui | Brazil | Details | |||
| Instituto de Cancer de Londrina | Londrina | Brazil | Details | |||
| Liga Norte-Rio-Grandense Contra o Câncer | Natal | Brazil | Details | |||
| HGB - Hospital Giovanni Battista - Mãe de Deus Center | Porto Alegre | Brazil | Details | |||
| Hospital de Clínicas de Porto Alegre | Porto Alegre | Brazil | Details | |||
| Irmandade da Santa Casa de Misericórdia de Porto Alegre | Porto Alegre | Brazil | Details | |||
| Grupo Oncoclínicas | Rio de Janeiro | Brazil | Details | |||
| INCA - Instituto Nacional de Câncer | Rio de Janeiro | Brazil | Details | |||
| Hospital Santa Izabel - Santa Casa de Misericórdia da Bahia | Salvador | Brazil | Details | |||
| CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia - Faculdade de Medicina do ABC | Santo André | Brazil | Details | |||
| BP A Beneficencia Portuguesa da Sao Paulo | São Paulo | Brazil | Details | |||
| ICESP - Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira | São Paulo | Brazil | Details | |||
| Centre Hospitalier de l'Universite de Montreal. | Montreal | Canada | Details | |||
| Beijing Cancer Hospital | Beijing | China | Details | |||
| Hospital of Bengbu Medical College | Bengbu | China | Details | |||
| The First Hospital of Jilin University | Changchun | China | Details | |||
| Hunan Cancer Hospital | Changsha | China | Details | |||
| Xiangya Hospital, Central South University | Changsha | China | Details | |||
| Sichuan Cancer Hospital | Chengdu | China | Details | |||
| West China Hospital, Sichuan University | Chengdu | China | Details | |||
| Chongqing University Cancer Hospital | Chongqing | China | Details | |||
| Fujian Cancer Hospital | Fuzhou | China | Details | |||
| Sun Yat-sen University Cancer Center | Guangzhou | China | Details | |||
| Sir Run Shaw Hospital, Zhejiang University, School of Medicine | Hangzhou | China | Details | |||
| Zhejiang Cancer Hospital | Hangzhou | China | Details | |||
| Anhui Provincial Cancer Hospital | Hefei | China | Details | |||
| Shandong Cancer Hospital | Jinan | China | Details | |||
| Jiangxi Cancer Hospital | Nanchang | China | Details | |||
| Nanjing Drum Tower Hospital | Nanjing | China | Details | |||
| Guangxi Medical University Affiliated Tumor Hospital | Nanning | China | Details | |||
| Fudan University Shanghai Cancer Center | Shangai | China | Details | |||
| Shanghai General Hospital | Shanghai | China | Details | |||
| Shengjing Hospital of China Medical University | Shenyang | China | Details | |||
| Tianjin Medical University Cancer Institute & Hospital | Tianjin | China | Details | |||
| Union Hospital, Tongji Medical College of Huazhong University of Science & Technology | Wuhan | China | Details | |||
| The Second Affiliated Hospital of Xi'an Jiaotong University（Xibei Hospital) | Xi'an | China | Details | |||
| Northern Jiangsu People's Hospital | Yangzhou | China | Details | |||
| Henan Cancer Hospital | Zhengzhou | China | Details | |||
| Fakultni nemocnice Olomouc - Dept of Onkologicka klinika | Olomouc | Czechia | Details | |||
| Fakultni nemocnice Kralovske Vinohrady - Dept of Radioterapeuticka a onkologicka klinika | Praha 10 | Czechia | Details | |||
| Fakultni nemocnice Bulovka - Dept of Radiodiagnosticka klinika | Praha | Czechia | Details | |||
| ICO - Site Paul Papin - service d'oncologie medicale | Angers Cedex 2 | France | Details | |||
| CHU Bordeaux - Service d'Oncologie Médicale | Bordeaux | France | Details | |||
| CHU Brest - Hôpital Morvan - Service d'Oncologie Médicale | Brest Cedex | France | Details | |||
| Centre Francois Baclesse - Service d'Oncologie Medicale | Caen Cedex 05 | France | Details | |||
| Centre Georges François Leclerc - Oncologie Médicale | Dijon | France | Details | |||
| Hopital Prive Drome Ardeche - Service D Oncologie | Guilherand Granges | France | Details | |||
| Clinique Victor Hugo - Centre Jean Bernard - Service d'Oncologie Médicale | Le Mans Cedex 02 | France | Details | |||
| Clinique Victor Hugo - Centre Jean Bernard - Service d'Oncologie Médicale | Le Mans | France | Details | |||
| Centre Oscar Lambret - service de cancerologie gynecologique | Lille cedex | France | Details | |||
| Centre Hospitalier de Bretagne Sud | Lorient cedex | France | Details | |||
| Centre Hospitalier de la Croix Rousse - Service ORL et chirurgie cervico-faciale | Lyon | France | Details | |||
| Hôpital de la Timone - Oncologie Médicale Hématologie & Soins Palliatifs | Marseille Cedex 5 | France | Details | |||
| Institut Régional du Cancer de Montpellier - Service de Professeur Senesse | Montpellier | France | Details | |||
| Centre Azureen Cancerologie - Service De Radiotherapie | Mougins | France | Details | |||
| Centre Antoine Lacassagne - Service d'Hématologie Oncologie | Nice cedex 02 | France | Details | |||
| Institut Curie - site de Paris - Service d'Oncologie Médicale | Paris Cedex 05 | France | Details | |||
| Hopital Tenon - service radiologie et imagerie medicale | Paris cedex | France | Details | |||
| CHU Poitiers - Hôpital la Milétrie - service d'oncologie médicale | Poitiers | France | Details | |||
| Centre Henri Becquerel - Service de radiothérapie | Rouen | France | Details | |||
| Centre Hospitalier Privé Saint-Gregoire (Rennes) - Cancerologie | Saint Grégoire | France | Details | |||
| ICO - Site René Gauducheau - Service d'Oncologie medicale | Saint Herblain | France | Details | |||
| Institut de Cancérologie de Strasbourg Europe - ICANS - Service d'oncologie médicale | Strasbourg Cedex | France | Details | |||
| CHI Toulon La Seyne - Hôpital Sainte Musse - Service d'Onco-Hematologie | Toulon cedex | France | Details | |||
| Institut Claudius Regaud - service de Radiothérapie | Toulouse cedex 09 | France | Details | |||
| CHU Tours - Hôpital Bretonneau - Service d'Oncologie Médicale | Tours | France | Details | |||
| Institut Gustave Roussy - Oncologie Médicale | Villejuif cedex | France | Details | |||
| High Technology Hospital Medcenter LLC | Batumi | Georgia | Details | |||
| JSC EVEX Hospitals | Kutaisi | Georgia | Details | |||
| Cancer Research Center Ltd. | Tbilisi | Georgia | Details | |||
| High Technology Medical Center, University Clinic | Tbilisi | Georgia | Details | |||
| LLC Todua Clinic | Tbilisi | Georgia | Details | |||
| New Hospitals | Tbilisi | Georgia | Details | |||
| Vivantes Klinikum Neukoelln - Parent | Berlin | Germany | Details | |||
| Universitaetsklinikum Giessen und Marburg GmbH Standort Giessen - Hals-, Nasen- und Ohrenklinik | Giessen | Germany | Details | |||
| Universitaetsmedizin Goettingen - Georg-August-Universität | Goettingen | Germany | Details | |||
| Universitaetsklinikum Jena - HNO_Klinik | Jena | Germany | Details | |||
| Universitaetsklinikum Schleswig-Holstein - Campus Kiel - Klinik für diagnostische Radiologie | Kiel | Germany | Details | |||
| Universitaetsklinikum Leipzig - Klinik fuer Strahlentherapie und Radioonkologie | Leipzig | Germany | Details | |||
| Universitaetsmedizin Rostock - Klinik und Poliklinik für Strahlentherapie | Rostock | Germany | Details | |||
| General Hospital of Athens of Chest Diseases "SOTIRIA" - Sotiria Thoracic Diseases Hospital of Athens | Athens | Greece | Details | |||
| University General Hospital "Attikon" | Athens | Greece | Details | |||
| Interbalkan Hospital of Thessaloniki | Thessaloniki | Greece | Details | |||
| Tata Medical Centre | Kolkata | India | Details | |||
| National Cancer Institute Nagpur | Nagpur | India | Details | |||
| All India Institute of Medical Sciences | New Delhi | India | Details | |||
| Regional Cancer Centre | Thiruvananthapuram | India | Details | |||
| Soroka University Medical Center | Beer sheva | Israel | Details | |||
| Rambam Health Care Campus | Haifa | Israel | Details | |||
| Chaim Sheba Medical Center - pt | Ramat Gan | Israel | Details | |||
| Hadassah University Hospital - Ein Kerem | Yerushalayim | Israel | Details | |||
| Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (Presidio Spedali Civili) - Oncologia Medica | Brescia | Italy | Details | |||
| Ospedale Oncologico Armando Businco - Divisione di Oncologia Medica II | Cagliari | Italy | Details | |||
| Fondazione del Piemonte per l'Oncologia IRCC Candiolo - Div. di Oncologia Medica ed Ematologia | Candiolo | Italy | Details | |||
| Azienda Ospedaliera Universitaria Careggi - S.O.D. di Oncologia Medica | Firenze | Italy | Details | |||
| IRCCS Istituto Scientifico Romagnolo Per Lo Studio e La Cura Dei Tumori "Dino Amadori" - IRST - U. Operativa di Immunoterapia e Terapia Cellulare | Meldola | Italy | Details | |||
| Fondazione IRCCS Istituto Nazionale dei Tumori - S.S. Tumori della Testa e del Collo | Milano | Italy | Details | |||
| IEO Istituto Europeo di Oncologia - Divisione Oncologia Medica | Milano | Italy | Details | |||
| Ospedale San Raffaele - U.O. di Oncologia Medica | Milano | Italy | Details | |||
| A.O.U. Policlinico di Modena - U.O. Oncologia | Modena | Italy | Details | |||
| Azienda Ospedaliera Universitaria- Università degli Studi della Campania "Luigi Vanvitelli" - Dipartimento Oncologia | Napoli | Italy | Details | |||
| Istituto Nazionale Tumori Fondazione G. Pascale - Oncologia Medica A | Napoli | Italy | Details | |||
| IOV - Istituto Oncologico Veneto IRCCS - Oncologia Medica 2 | Padova | Italy | Details | |||
| Azienda Ospedaliera Universitaria Policlinico Umberto I - Università di Roma La Sapienza - U.O.C. di Oncologia B | Roma | Italy | Details | |||
| Fondazione Policlinico Universitario Agostino Gemelli IRCCS - UOC Radioterapia 1 | Roma | Italy | Details | |||
| Istituto Clinico Humanitas - U.O. di Oncologia Medica ed Ematologia | Rozzano | Italy | Details | |||
| Hyogo Cancer Center - Dept of Head and Neck Surgery | Akashi-shi | Japan | Details | |||
| National Cancer Center Hospital - Dept of Gastroenterology | Chuo-ku | Japan | Details | |||
| NHO Kyushu Cancer Center - Dept of Head and Neck Surgery | Fukuoka-shi | Japan | Details | |||
| Saitama Medical University International Medical Center - Dept of Otorhinolaryngology/ Head and Neck Surgery | Hidaka-shi | Japan | Details | |||
| Hiroshima University Hospital - Dept of Otorhinolaryngology/ Head and Neck Surgery | Hiroshima-shi | Japan | Details | |||
| National Cancer Center Hospital East - Dept of Head and Neck Medical Oncology | Kashiwa-shi | Japan | Details | |||
| Kagawa University Hospital - Dept of Oncology | Kita-gun | Japan | Details | |||
| Saitama Cancer Center - Dept of Head and Neck Surgery | Kitaadachi-gun | Japan | Details | |||
| Kobe University Hospital - Dept of Oncology/Hematology | Kobe-shi | Japan | Details | |||
| Cancer Institute Hospital of JFCR - Dept of Medical Oncology | Koto-ku | Japan | Details | |||
| NHO Shikoku Cancer Center - Dept of Head and Neck Surgery | Matsuyama-shi | Japan | Details | |||
| Aichi Cancer Center Hospital - Dept of Head and Neck Surgery | Nagoya-shi | Japan | Details | |||
| Nagoya University Hospital - Dept of Otorhinolaryngology | Nagoya-shi | Japan | Details | |||
| Okayama University Hospital - Dept of Otorhinolaryngology | Okayama-shi | Japan | Details | |||
| Osaka International Cancer Institute - Dept of Head and Neck Surgery | Osaka-shi | Japan | Details | |||
| Kindai University Hospital - Dept of Oncology | Osakasayama-shi | Japan | Details | |||
| Hokkaido University Hospital - Dept of Otorhinolaryngology | Sapporo-shi | Japan | Details | |||
| NHO Hokkaido Cancer Center - Dept of Oral Oncology Surgery | Sapporo-shi | Japan | Details | |||
| Tohoku University Hospital - Dept of Otorhinolaryngology/Head and Neck Surgery | Sendai-shi | Japan | Details | |||
| Yokohama City University Hospital - Dept of Otorhinolaryngology | Yokohama-shi | Japan | Details | |||
| Chonnam National University Hwasun Hospital | Hwasun-gun | Korea, Republic of | Details | |||
| Seoul National University Bundang Hospital | Seongnam | Korea, Republic of | Details | |||
| Konkuk University Medical Center | Seoul | Korea, Republic of | Details | |||
| Severance Hospital, Yonsei University Health System | Seoul | Korea, Republic of | Details | |||
| The Catholic University of Korea, St. Vincent's Hospital | Suwon-si | Korea, Republic of | Details | |||
| Pusan National University Yangsan Hospital | Yangsan-si | Korea, Republic of | Details | |||
| Hospital Civil Fray Antonio Alcalde - O.P.D. Hospital Civil de Guadalajara | Guadalajara | Mexico | Details | |||
| Centro de Atención e Investigación Clínica en Oncología | Merida | Mexico | Details | |||
| Universidad Autonoma de Nuevo Leon, Hospital Universitario Dr. Jose Eleuterio Gonzalez | Monterrey | Mexico | Details | |||
| Amsterdam UMC, Locatie VUMC - Dept of Medical Oncology | Amsterdam | Netherlands | Details | |||
| Universitair Medisch Centrum Groningen - Cancer Center | Groningen | Netherlands | Details | |||
| UMC Utrecht - Dept Medical Oncology | Utrecht | Netherlands | Details | |||
| Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie, Państwowy Instytut Badawczy - Zakład Medycyny Nuklearnej i Endokrynologii Onkolo | Gliwice | Poland | Details | |||
| Hospital de Braga - Serviço de Oncologia Medica | Braga | Portugal | Details | |||
| Instituto Português de Oncologia do Porto Francisco Gentil, EPE | Porto | Portugal | Details | |||
| Centrul medical Focus | Bucuresti | Romania | Details | |||
| S.C Medisprof S.R.L - parent | Cluj-Napoca | Romania | Details | |||
| S.C Radiotherapy Center Cluj S.R.L - Parent | ComunaFloresti | Romania | Details | |||
| S.C Centrul de Oncologie Sf. Nectarie S.R.L - parent | Craiova | Romania | Details | |||
| S.C Oncocenter Oncologie Clinica S.R.L - parent | Timisoara | Romania | Details | |||
| Complejo Hospitalario Universitario A Coruña - CHUAC-Hospital Teresa Herrera | A Coruña | Spain | Details | |||
| Complejo Hospitalario Universitario A Coruña - Servicio de Oncologia | A Coruña | Spain | Details | |||
| Hospital Clinic de Barcelona - Medical Oncology | Barcelona | Spain | Details | |||
| Hospital del Mar - Servicio de Oncologia | Barcelona | Spain | Details | |||
| Hospital Universitari Vall d'Hebron - Oncology Dept. | Barcelona | Spain | Details | |||
| ICO Badalona - Hospital Universitari Germans Trias i Pujol - Servicio de Oncologia Medica | Barcelona | Spain | Details | |||
| ICO l'Hospitalet - Hospital Duran i Reynals - Servicio de Oncologia | Barcelona | Spain | Details | |||
| Complejo Hospitalario Universitario Insular Materno-Infantil - Servicio de Oncologia | Las Palmas de Gran Canaria | Spain | Details | |||
| Hospital Universitario Lucus Augusti - Oncology | Lugo | Spain | Details | |||
| Clinica Universidad de Navarra (MAD) - Oncology Service | Madrid | Spain | Details | |||
| Hospital Universitario Fundacion Jimenez Diaz - Oncology | Madrid | Spain | Details | |||
| Hospital Universitario La Paz - Oncology Department | Madrid | Spain | Details | |||
| Hospital Regional Universitario de Malaga - Oncology Dept | Málaga | Spain | Details | |||
| Hospital Universitario Virgen del Rocio - Oncology Service | Sevilla | Spain | Details | |||
| Universitaetsspital Basel - Klinik fuer Strahlentherapie und Radioonkologie | Basel | Switzerland | Details | |||
| Istituto Oncologico della Svizzera Italiana (IOSI)- Ente Ospedaliero Cantonale (EOC) - Ospedale S.Giovanni | Bellinzona | Switzerland | Details | |||
| CHUV, Lausanne University Hospital | Lausanne | Switzerland | Details | |||
| Universitaetsspital Zuerich - Parent | Zuerich | Switzerland | Details | |||
| Changhua Christian Medical Foundation Changhua Christian Hospital | ChangHua | Taiwan | Details | |||
| Kaohsiung Chang Gung Memorial Hospital | Kaohsiung | Taiwan | Details | |||
| Kaohsiung Medical University Chung-Ho Memorial Hospital | Kaohsiung | Taiwan | Details | |||
| China Medical University Hospital | Taichung | Taiwan | Details | |||
| Chi Mei Hospital, Liouying | Tainan | Taiwan | Details | |||
| National Cheng Kung University Hospital | Tainan | Taiwan | Details | |||
| Taipei Veterans General Hospital | Taipei City | Taiwan | Details | |||
| National Taiwan University Hospital | Taipei | Taiwan | Details | |||
| Chang Gung Memorial Hospital,Linkou | Taoyuan | Taiwan | Details | |||
| St James's University Hospital - Dept of Oncology | Leeds | United Kingdom | Details | |||
| Royal Marsden Hospital-London - Dept of Haematology/Oncology Research | London | United Kingdom | Details | |||
| The Christie Hospital - Dept of Oncology | Manchester | United Kingdom | Details | |||
| Mount Vernon Cancer Centre | Northwood | United Kingdom | Details | |||
| Musgrove Park Hospital - PARENT | Somerset | United Kingdom | Details | |||
| The Royal Marsden NHS Foundation Trust | Sutton | United Kingdom | Details | |||
| Torbay Hospital - PARENT | Torquay | United Kingdom | Details | |||
| Clatterbridge Cancer Centre | Wirral | United Kingdom | Details |