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| NCT ID | NCT06353386 |
| Title | Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase Ib/II |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme LLC |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | POL | NZL | ITA | ISR | IRL | GBR | FRA | FIN | ESP | DNK | DEU | CAN | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Aalborg Universitetshospital, Syd ( Site 0503) | RECRUITING | Aalborg | Nordjylland | 9000 | Denmark | Details |
| Addenbrooke's Hospital ( Site 1902) | RECRUITING | Cambridge | Cambridgeshire | CB2 2QQ | United Kingdom | Details |
| Ankara Bilkent Şehir Hastanesi ( Site 1801) | RECRUITING | Ankara | 06800 | Turkey | Details | |
| Asan Medical Center-Oncology ( Site 1500) | RECRUITING | Songpagu | Seoul | 05505 | Korea, Republic of | Details |
| Auckland City Hospital ( Site 1333) | RECRUITING | Auckland | 1023 | New Zealand | Details | |
| Azienda Ospedaliera Universitaria Integrata Verona - Ospedale Borgo Roma-Oncology Unit ( Site 1100) | RECRUITING | Verona | Veneto | 37134 | Italy | Details |
| Baskent University Dr. Turgut Noyan Research and Training Center-ONCOLOGY ( Site 1802) | RECRUITING | Adana | 01250 | Turkey | Details | |
| Bradfordhill ( Site 0300) | RECRUITING | Santiago | Region M. De Santiago | 8420383 | Chile | Details |
| Centre Hospitalier de l'Université de Montréal ( Site 0200) | RECRUITING | Montréal | Quebec | H2X 3E4 | Canada | Details |
| Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 0207) | RECRUITING | Quebec | G1J 1Z4 | Canada | Details | |
| Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 1402) | RECRUITING | Bydgoszcz | Kujawsko-pomorskie | 85-796 | Poland | Details |
| Chang Gung Medical Foundation-Linkou Branch-Medical Oncology ( Site 1702) | RECRUITING | Taoyuan | 333 | Taiwan | Details | |
| Chang Gung Memorial Hospital at Kaohsiung-Oncology and Hematology ( Site 1704) | RECRUITING | Kaohsiung Niao Sung Dist | Kaohsiung | 83301 | Taiwan | Details |
| Charité Universitaetsmedizin Berlin - Campus Mitte ( Site 0800) | RECRUITING | Berlin | 10117 | Germany | Details | |
| China Medical University Hospital ( Site 1703) | RECRUITING | Taichung | 404332 | Taiwan | Details | |
| CIDO SpA-Oncology ( Site 0302) | RECRUITING | Temuco | Biobio | 4810218 | Chile | Details |
| Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia ( Site 0402) | RECRUITING | Bogota | Distrito Capital De Bogota | 111321 | Colombia | Details |
| Clinica Universidad Catolica del Maule-Oncology ( Site 0304) | RECRUITING | Talca | Maule | 3465584 | Chile | Details |
| Cork University Hospital ( Site 0902) | RECRUITING | Cork | T12 E8YV | Ireland | Details | |
| Docrates Syöpäsairaala ( Site 0602) | RECRUITING | Helsinki | Uusimaa | 00180 | Finland | Details |
| FALP ( Site 0301) | RECRUITING | Santiago | Region M. De Santiago | 7500921 | Chile | Details |
| Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1103) | RECRUITING | Milan | Lombardia | 20133 | Italy | Details |
| Fondazione Policlinico Universitario Agostino Gemelli IRCCS -Medical Oncology ( Site 1102) | RECRUITING | Roma | Lazio | 00168 | Italy | Details |
| FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0406) | RECRUITING | Bogota | Distrito Capital De Bogota | 110131 | Colombia | Details |
| Fundación Valle del Lili-Oncology CIC ( Site 0403) | RECRUITING | Cali | Valle Del Cauca | 760032 | Colombia | Details |
| Gallipoli Medical Research Ltd-GMRF CTU ( Site 0107) | RECRUITING | Greenslopes | Queensland | 4120 | Australia | Details |
| Gustave Roussy ( Site 0701) | RECRUITING | Villejuif | Ile-de-France | 94805 | France | Details |
| Hacettepe Universite Hastaneleri-oncology hospital ( Site 1800) | RECRUITING | Ankara | 06230 | Turkey | Details | |
| Helsinki University Hospital - Comprehensive Cancer Center (HYKS - Syöpäkeskus) ( Site 0604) | RECRUITING | Helsinki | Uusimaa | 00029 | Finland | Details |
| Herlev and Gentofte Hospital ( Site 0501) | RECRUITING | Copenhagen | Hovedstaden | 2730 | Denmark | Details |
| Hospital Clinico San Carlos-Oncology Department ( Site 1604) | RECRUITING | Madrid | 28040 | Spain | Details | |
| Hospital General Universitario Gregorio Marañón ( Site 1601) | RECRUITING | Madrid | 28007 | Spain | Details | |
| Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 1602) | RECRUITING | Barcelona | 08035 | Spain | Details | |
| Hospital Universitario Ramón y Cajal-Medical Oncology ( Site 1600) | RECRUITING | Madrid | Madrid, Comunidad De | 28034 | Spain | Details |
| Hôpital Européen Georges Pompidou-Service d'Oncologie Médicale ( Site 0702) | RECRUITING | Paris | 75015 | France | Details | |
| IMAT S.A.S ( Site 0404) | RECRUITING | Monteria | Cordoba | 230002 | Colombia | Details |
| Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest ( Site 0703) | RECRUITING | Bordeaux | Aquitaine | 33076 | France | Details |
| Institut Català d'Oncologia - L'Hospitalet-Medical Oncology ( Site 1603) | RECRUITING | L Hospitalet | Barcelona | 08908 | Spain | Details |
| Institut de cancérologie Strasbourg Europe (ICANS) ( Site 0700) | RECRUITING | Strasbourg | Alsace | 67200 | France | Details |
| Istanbul Universitesi Cerrahpasa-Medical Oncology ( Site 1804) | RECRUITING | Istanbul | 34668 | Turkey | Details | |
| Istituto Clinico Humanitas-U.O di Oncologia medica ed Ematologia ( Site 1101) | RECRUITING | Rozzano | Milano | 20089 | Italy | Details |
| Jewish General Hospital ( Site 0206) | RECRUITING | Montreal | Quebec | H3T 1E2 | Canada | Details |
| klinikum rechts der isar der technischen universität münchen-Urologische Klinik und Poliklinik ( Site 0802) | RECRUITING | Munich | Bayern | 81675 | Germany | Details |
| Kyushu University Hospital ( Site 1204) | RECRUITING | Fukuoka | 812-8582 | Japan | Details | |
| Macquarie University-MQ Health Clinical Trials Unit ( Site 0108) | RECRUITING | Macquarie University | New South Wales | 2109 | Australia | Details |
| MEDICAL COLLEGE OF WISCONSIN-Cancer Center Clinical Trials Office ( Site 0020) | RECRUITING | Milwaukee | Wisconsin | 53226 | United States | Details |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Oddzial Badan Wczesnych Faz ( Site 1400) | RECRUITING | Warszawa | Mazowieckie | 02-781 | Poland | Details |
| Peter MacCallum Cancer Centre-Parkville Cancer Clinical Trials Unit (PCCTU) ( Site 0110) | RECRUITING | Melbourne | Victoria | 3000 | Australia | Details |
| Pontificia Universidad Catolica de Chile-Centro del Cáncer ( Site 0303) | RECRUITING | Santiago | Region M. De Santiago | 8330024 | Chile | Details |
| Queen Elizabeth Hospital Birmingham ( Site 1903) | RECRUITING | Birmingham | Warwickshire | B15 2TH | United Kingdom | Details |
| Rabin Medical Center ( Site 1001) | RECRUITING | Petah Tikva | 4941492 | Israel | Details | |
| Rambam Health Care Campus-Oncology Division ( Site 1002) | RECRUITING | Haifa | 3109601 | Israel | Details | |
| Royal Preston Hospital-Lancashire Clinical Research Facility ( Site 1900) | RECRUITING | Preston | Lancashire | PR2 9HT | United Kingdom | Details |
| Rutgers Cancer Institute of New Jersey ( Site 0033) | RECRUITING | New Brunswick | New Jersey | 08903-2681 | United States | Details |
| Samsung Medical Center-Division of Hematology/Oncology ( Site 1501) | RECRUITING | Seoul | 06351 | Korea, Republic of | Details | |
| Severance Hospital, Yonsei University Health System-Medical oncology ( Site 1502) | RECRUITING | Seoul | 03722 | Korea, Republic of | Details | |
| Sheba Medical Center ( Site 1000) | RECRUITING | Ramat Gan | 5265601 | Israel | Details | |
| Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 0400) | RECRUITING | Valledupar | Cesar | 200001 | Colombia | Details |
| St. Vincent's University Hospital ( Site 0901) | RECRUITING | Dublin 4 | Dublin | D04 T6F4 | Ireland | Details |
| Taipei Veterans General Hospital ( Site 1701) | RECRUITING | Taipei | 112 | Taiwan | Details | |
| Tallaght University Hospital ( Site 0900) | RECRUITING | Dublin | D24 NR0A | Ireland | Details | |
| TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 1803) | RECRUITING | Istanbul | 34722 | Turkey | Details | |
| The Beatson West of Scotland Cancer Centre ( Site 1904) | RECRUITING | Glasgow | Glasgow City | G12 0YN | United Kingdom | Details |
| The Jikei University Hospital ( Site 1202) | RECRUITING | Mitato | Tokyo | 105-8471 | Japan | Details |
| Toho University Sakura Medical Center ( Site 1201) | RECRUITING | Sakura | Chiba | 285-8741 | Japan | Details |
| UCLA Hematology/Oncology - Santa Monica ( Site 0044) | RECRUITING | Los Angeles | California | 90404 | United States | Details |
| UCSD Moores Cancer Center ( Site 0039) | RECRUITING | La Jolla | California | 92037 | United States | Details |
| Universitaetsklinikum Hamburg-Eppendorf-Onkologisches Zentrum ( Site 0804) | RECRUITING | Hamburg | 20246 | Germany | Details | |
| Universitaetsklinikum Heidelberg ( Site 0805) | RECRUITING | Heidelberg | Baden-Wurttemberg | 69120 | Germany | Details |
| Universitaetsklinikum Tuebingen-Urologie ( Site 0801) | RECRUITING | Tübingen | Baden-Wurttemberg | 72076 | Germany | Details |
| University College London Hospital ( Site 1905) | RECRUITING | London | London, City Of | NW1 2PG | United Kingdom | Details |
| University Hospitals Cleveland Medical Center ( Site 0043) | RECRUITING | Cleveland | Ohio | 44106 | United States | Details |
| University of Maryland-Greenebaum Comprehensive Cancer Center ( Site 0049) | RECRUITING | Baltimore | Maryland | 21201 | United States | Details |
| University of Miami Hospital and Clinics, Sylvester Cancer Center-Cancer Research Services ( Site 0051) | RECRUITING | Miami | Florida | 33136 | United States | Details |
| Uniwersyteckie Centrum Kliniczne ( Site 1405) | RECRUITING | Gdansk | Pomorskie | 80-952 | Poland | Details |
| Vaasan Keskussairaala ( Site 0603) | RECRUITING | Vaasa | Pohjanmaa | 65130 | Finland | Details |
| Yokohama City University Medical Center ( Site 1203) | RECRUITING | Yokohama | Kanagawa | 232-0024 | Japan | Details |
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