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| ID | DOID:1752 |
| Name | ocular melanoma |
| Definition | An ocular cancer that has_material_basis_in melanocytes and is located_in the eye. |
| Source | DiseaseOntology.org |
| Alt Ids | |
| Path | disease disease of cellular proliferation cancer organ system cancer nervous system cancer sensory system cancer ocular cancer ocular melanoma |
| Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
|---|
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT01252251 | Phase II | Everolimus + Pasireotide | RAD001 (Everolimus) and Pasireotide (SOM230) LAR in Patients With Advanced Uveal Melanoma | Completed | USA | 0 |
| NCT01801358 | Phase Ib/II | Binimetinib Binimetinib + Sotrastaurin | A Phase Ib/II Study of AEB071 and MEK162 in Adult Patients With Metastatic Uveal Melanoma | Terminated | USA | NLD | GBR | FRA | ESP | DEU | 0 |
| NCT03528408 | Phase II | Ipilimumab + Nivolumab | Study of Adjuvant Ipilimumab and Nivolumab in Subjects With High-risk Ocular Melanoma | Unknown status | USA | 0 |
| NCT03865212 | Phase I | VSV-IFNbetaTYRP1 | Modified Virus VSV-IFNbetaTYRP1 in Treating Patients With Stage III-IV Melanoma | Active, not recruiting | USA | 0 |
| NCT04042506 | Phase II | Nivolumab | SBRT as a Vaccination for Metastatic Melanoma | Withdrawn | USA | 0 |
| NCT04328844 | Phase I | Roginolisib | A Study to Assess a PI3Kdelta Inhibitor (IOA-244) in Patients With Metastatic Cancers | Active, not recruiting | ITA | GBR | 0 |
| NCT04338685 | Phase I | RO7119929 + Tocilizumab | A Study Evaluating Safety, Pharmacokinetics, Pharmacodynamics, And Clinical Activity Of RO7119929 (TLR7 Agonist) In Participants With Unresectable Advanced Or Metastatic Hepatocellular Carcinoma, Biliary Tract Cancer, Or Solid Tumors With Hepatic Metastases | Completed | USA | ESP | DNK | 3 |
| NCT05628883 | Phase I | Cyclophosphamide + Fludarabine TBio-4101 Aldesleukin | Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma | Active, not recruiting | USA | 0 |
| NCT06717126 | Phase II | Roginolisib | A Randomised Phase II Study of Roginolisib in Patients with Advanced/metastatic Uveal Melanoma (OCULE-01) | Recruiting | ITA | GBR | ESP | 0 |
| NCT06961357 | Phase Ib/II | Interleukin-12 CD40L-augmented TILs Cyclophosphamide + Fludarabine | Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma | Recruiting | USA | 0 |