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ID DOID:314
Name tenosynovial giant cell tumor
Definition
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation benign neoplasm organ system benign neoplasm musculoskeletal system benign neoplasm connective tissue benign neoplasm bone benign neoplasm benign giant cell tumor tenosynovial giant cell tumor

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT01207492 Phase II Nilotinib Nilotinib in Patients With Relapsed or Metastatic Pigmented Villonodular Synovitis/Tenosynovial Giant Cell Tumor/Diffuse-Type Giant Cell Tumor Active, not recruiting USA 0
NCT02471716 Phase Ib/II Cabiralizumab Study of FPA008 in Patients With Pigmented Villonodular Synovitis / Diffuse Type Tenosynovial Giant Cell Tumor Completed USA | POL | NLD | GBR | FRA 1
NCT02673736 Phase I AC708 A Study of PLX73086 in Advanced Solid Tumors and Locally Advanced or Refractory Tenosynovial Giant Cell Tumor Terminated USA 0
NCT04526704 FDA approved Pexidartinib Study to Evaluate Discontinuation and Re-Treatment in Participants With Tenosynovial Giant Cell Tumor (TGCT) Previously Treated With Pexidartinib (PLX3397) Completed USA | NLD | ITA | HUN | ESP | AUS 1
NCT04938180 Phase II AMG 820 A Phase 2 Study of Intravenous AMB-05X in Tenosynovial Giant Cell Tumor Patients Terminated POL | HUN 1
NCT05059262 Phase III Vimseltinib Phase 3 Study of Vimseltinib for Tenosynovial Giant Cell Tumor (MOTION) Active, not recruiting USA | POL | NOR | NLD | ITA | GBR | FRA | ESP | DEU | CHE | CAN | AUS 1
NCT05349643 Phase II AMB-05X A Study to Evaluate Safety and Efficacy of AMB-05X Injections in Subjects With TGCT Completed USA | NLD | AUS 0
NCT05417789 Phase III Emactuzumab Study of Emactuzumab for Tenosynovial Giant Cell Tumor (TGCT) (TANGENT) Recruiting USA | NLD | ITA | ESP | CHE 1
NCT05804045 Phase III ABSK021 Study of Pimicotinib (ABSK021) for Tenosynovial Giant Cell Tumor Active, not recruiting USA | POL | NLD | ITA | ESP | CAN 1