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| ID | DOID:0050688 |
| Name | anal canal cancer |
| Definition | A large intestine cancer that is located_in the terminal part of the large intestine. |
| Source | DiseaseOntology.org |
| Alt Ids | |
| Path | disease disease of cellular proliferation cancer organ system cancer gastrointestinal system cancer intestinal cancer large intestine cancer anal canal cancer |
| Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
|---|
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT02399813 | Phase Ib/II | ADXS11-001 | Phase 2 Study of ADXS11-001 in Subjects With Anal Cancer or Cancer of the Rectum | Completed | USA | 0 |
| NCT02404441 | Phase Ib/II | Spartalizumab | Phase I/II Study of PDR001 in Patients With Advanced Malignancies | Completed | USA | TUR | POL | NOR | NLD | LBN | ITA | HUN | FRA | ESP | DEU | CAN | 2 |
| NCT02426892 | Phase II | Nivolumab | Nivolumab and HPV-16 Vaccination in Patients With HPV-16 Positive Incurable Solid Tumors | Completed | USA | 0 |
| NCT03427411 | Phase II | Bintrafusp alfa | Phase II Trial of M7824 in Subjects With HPV Positive Malignancies | Completed | USA | 0 |
| NCT03618953 | Phase I | Ad-E6E7 + Atezolizumab + MG1-E6E7 | This is a Trial of MG1-E6E7 With Ad-E6E7 and Atezolizumab in Patients With HPV Associated Cancers (Kingfisher) | Terminated | USA | CAN | 0 |
| NCT04157985 | Phase III | Nivolumab Ipilimumab Cemiplimab Pembrolizumab Atezolizumab | Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumors | Recruiting | USA | 0 |
| NCT06638931 | Phase II | Nivolumab | Agnostic Therapy in Rare Solid Tumors (ANTARES) | Active, not recruiting | BRA | 0 |
| NCT06640283 | Phase II | Pembrolizumab | Dynamic ctDNA Assessment in Cervical and Anal Canal Tumors: Optimizing Follow-up and Clinical Outcomes (ANA) | Not yet recruiting | BRA | 0 |