T-cell large granular lymphocyte leukemia
Disease Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

ID DOID:0050751
Name T-cell large granular lymphocyte leukemia
Definition A T-cell acute lymphocytic leukemia that exhibits an unexplained, chronic (greater than 6 months) elevation in large granular lymphocytes (LGLs) in the peripheral blood.
Source DiseaseOntology.org
Alt Ids
Xrefs
ICDO:9831/3
Path disease disease of cellular proliferation cancer organ system cancer hematologic cancer leukemia lymphoid leukemia acute leukemia acute lymphoblastic leukemia T-cell acute lymphoblastic leukemia T-cell large granular lymphocyte leukemia

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02512497 Phase I Romidepsin Busulfan + Fludarabine + Romidepsin Romidepsin Maintenance After Allogeneic Stem Cell Transplantation Completed USA 0
NCT03239392 Phase Ib/II BNZ-1 A Dose-Ranging Study of IV BNZ-1 in LGL Leukemia or Refractory CTCL Completed USA 0
NCT03829540 Phase I CD4CAR CD4CAR for CD4+ Leukemia and Lymphoma Recruiting USA 0
NCT05010005 Phase I Duvelisib + Ruxolitinib A Study of Ruxolitinib and Duvelisib in People With Lymphoma Recruiting USA 0
NCT05225584 Phase I KT-333 Safety, PK, PD, Clinical Activity of KT-333 in Adult Patients With Refractory Lymphoma, Large Granular Lymphocytic Leukemia, Solid Tumors Completed USA 0
NCT05316116 Phase I Siltuximab Siltuximab in Large Granular Lymphocytic Leukemia (LGLL) Terminated USA 0
NCT05475925 Phase Ib/II DR-01 A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas Recruiting USA | ITA | FRA | ESP | DEU | AUS 3
NCT05532722 Phase Ib/II ABC008 ABC008 in Subjects With T-cell Large Granular Lymphocytic Leukemia (T-LGLL) Active, not recruiting USA 0
NCT05592015 Phase II Ruxolitinib Ruxolitinib for the Treatment of T-Cell Large Granular Lymphocytic Leukemia Recruiting USA 0