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ID | DOID:60074 |
Name | ductal carcinoma in situ |
Definition | A breast carcinoma in situ that is characterized by being non-invasive, not having spread outside of the duct into the surrounding breast tissue, has_material_basis_in abnormally proliferating cells, derives_from epithelial cells. |
Source | DiseaseOntology.org |
Alt Ids | |
Path | disease disease of cellular proliferation pre-malignant neoplasm in situ carcinoma breast carcinoma in situ ductal carcinoma in situ |
Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT01097278 | Phase 0 | Cholecalciferol | S0812 High Dose Cholecalciferol in Premenopausal Women at High-Risk for Breast Cancer | Completed | USA | 0 |
NCT02540330 | Phase II | Fulvestrant | A Pre-Surgical PK Study of IM and Intraductally Delivered Fulvestrant (007) | Terminated | USA | 0 |
NCT02636582 | Phase II | Sargramostim Nelipepimut-S Plus GM-CSF | Nelipepimut-S Plus GM-CSF Vaccine Therapy in Treating Patients With Breast Cancer | Completed | USA | 0 |
NCT02694809 | Phase II | Conjugated estrogens-bazedoxifene | Conjugated Estrogens/Bazedoxifene in Treating Patients With Ductal Carcinoma in Situ Undergoing Surgery | Recruiting | USA | 0 |
NCT02872025 | Phase I | Pembrolizumab | Pembrolizumab in High-risk Ductal Carcinoma in Situ (DCIS) | Recruiting | USA | 0 |
NCT02928978 | Phase II | Ruxolitinib | Ruxolitinib for Premalignant Breast Disease | Recruiting | USA | 0 |
NCT02993159 | Phase II | Afimoxifene Tamoxifen | Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through the Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast | Recruiting | USA | 0 |
NCT03535506 | Phase II | Palbociclib | Preoperative Palbociclib in Patients With DCIS of the Breast That Are Candidates for Surgery (WI223281) | Terminated | USA | 0 |
NCT04666961 | Phase II | Anastrozole + Tamoxifen | Impact of Neoadjuvant Hormonal Therapy on the Surgical Management of Extensive Ductal Carcinomas in Situ (HORNEO01) | Recruiting | FRA | 0 |