oropharyngeal squamous cell carcinoma
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ID DOID:0070664
Name oropharyngeal squamous cell carcinoma
Definition An oropharynx cancer that derives_from squamous epithelial cells.
Source DiseaseOntology.org
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SNOMEDCT_US_2025_09_01:423464009
Path disease disease of cellular proliferation cancer organ system cancer gastrointestinal system cancer pharynx cancer oropharynx cancer oropharyngeal squamous cell carcinoma

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05176483 Phase I XL092 Ipilimumab + Nivolumab + XL092 Nivolumab and relatlimab-rmbw + XL092 Nivolumab + XL092 Ipilimumab + Nivolumab Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors (STELLAR-002) Active, not recruiting USA | POL | NZL | ITA | ISR | GBR | FRA | ESP | DEU | CHE | BEL | AUT | AUS 0
NCT06727565 Phase II Carboplatin + Paclitaxel + Zimberelimab AB154 + Carboplatin + Paclitaxel + Zimberelimab Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status; Substudy-01 (VELOCITY-HNSCC) Recruiting USA | ITA | GBR | FRA | ESP | AUS 3
NCT06980038 Phase II CDX-1140 + Cemiplimab Cemiplimab Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer Recruiting USA 0
NCT07276399 Phase III Cisplatin + Fluorouracil + Pembrolizumab Carboplatin + Fluorouracil + Pembrolizumab Amivantamab-vmjw + Carboplatin + Pembrolizumab A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer (OrigAMI-5) Recruiting USA | GBR | BRA | AUS 3
NCT07346196 Phase II Carboplatin + Cemiplimab + Fianlimab + Paclitaxel Carboplatin + Cemiplimab + Paclitaxel A Randomized Phase II Trial of Locoregionally Advanced Squamous Cell Carcinoma of The Head and Neck Not yet recruiting USA 0