posterior fossa group A ependymoma
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ID DOID:0081254
Name posterior fossa group A ependymoma
Definition A posterior fossa ependymoma that arises in the posterior fossa with characteristic DNA methylation patterns, including CpG island hypermethylation, global DNA hypomethylation, reduction of nuclear H3 p.K28me3 (K27me3) expression, and EZHIP overexpression.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer cell type cancer high grade glioma high grade ependymoma posterior fossa ependymoma posterior fossa group A ependymoma

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT07226453 Phase II Metformin Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma (PNOC041) Not yet recruiting USA 0