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ID DOID:81282
Name oligodendroglioma, IDH-mutant and 1p/19q-codeleted, grade 3
Definition An IDH-mutant, and 1p/19q-codeleted oligodendroglioma that is characterized as grade 3 tumors associated with a more rapid growth. Grade 3 tumors appear to have abnormalities on chromosomes 9 or 10, along with unusual amounts of growth factors and proteins, which are thought to contribute to the more rapid growth of these gliomas.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer cell type cancer high grade glioma oligodendroglioma anaplastic oligodendroglioma IDH-mutant and 1p/19q-codeleted oligodendroglioma oligodendroglioma, IDH-mutant and 1p/19q-codeleted, grade 3

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05804227 Phase I Ulixertinib Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Low-Grade Gliomas in Adults Recruiting USA 0
NCT06478212 Phase Ib/II Temozolomide + Vorasidenib Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant Glioma Not yet recruiting USA | NLD | ITA | ISR | GBR | FRA | ESP | DEU | AUT 2