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| Drug Name | CD5 CAR-T cells |
| Trade Name | |
| Synonyms | autologous CD5.CAR/28zeta CAR T cells|Anti-CD5 CAR T cells |
| Drug Descriptions |
CD5 CAR-T cells are autologous T-cells engineered to express a chimeric antigen receptor (CAR) targeting CD5 fused to the intracellular signaling domain of CD28 and the T-cell receptor (TCR) zeta chain, which potentially induce toxicity against CD5-expressing tumor cells and inhibit tumor growth (PMID: 26056165). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C148490 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CD5 CAR-T cells | CD5 CAR-T cells | 0 | 1 |
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