NC318
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| Drug Name | NC318 |
| Trade Name | |
| Synonyms | NC-318|NC 318|Anti-S15 mAb NC318 |
| Drug Descriptions |
NC318 is a monoclonal antibody that binds to sialic acid binding Ig-like lectin 15 (Siglec-15) expressed on tumor-associated macrophages, which may disrupt T-cell response inhibition, leading to antitumor activity (PMID: 31806628). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C157061 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| NC318 | NC318 | 0 | 2 |
| NC318 + Pembrolizumab | NC318 Pembrolizumab | 0 | 1 |
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