Anti-CD37 CAR T cells
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| Drug Name | Anti-CD37 CAR T cells |
| Trade Name | |
| Synonyms | CAR-37 T cells|Anti-CD37-CAR-expressing T-lymphocytes |
| Drug Descriptions |
Anti-CD37 CAR T cells consist of T-lymphocytes engineered to express a chimeric antigen receptor (CAR) that targets CD37 and contains a CD8 transmembrane domain linked to CD137 (4-1BB) and CD3 zeta signaling domains, which potentially induces cytotoxicty against tumor cells expressing CD37, and reduces tumor burden (PMID: 30089630). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C171034 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Anti-CD37 CAR T cells | Anti-CD37 CAR T cells | 0 | 1 |
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