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Drug Name | CLL-1 CAR-T cells |
Trade Name | |
Synonyms | CLL1 CAR-T cells|anti-CLL1 CART cells |
Drug Descriptions |
CLL-1 CAR-T cells consist of T-lymphocytes engineered to express a chimeric antigen receptor (CAR) that targets CLL1 and contains CD28 and CD137 (4-1BB) costimulatory and CD3 zeta signaling domains, which potentially induces lysis of tumor cells expressing CLL1 and reduces tumor burden (PMID: 29316944). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CLL-1 CAR-T cells | CLL-1 CAR-T cells | 0 | 1 |