Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Therapy Name | CLL-1 CAR-T cells |
Synonyms | |
Therapy Description |
CLL-1 CAR-T cells consist of T-lymphocytes engineered to express a chimeric antigen receptor (CAR) that targets CLL1 and contains CD28 and CD137 (4-1BB) costimulatory and CD3 zeta signaling domains, which potentially induces lysis of tumor cells expressing CLL1 and reduces tumor burden (PMID: 29316944). |