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Drug Name | Brequinar |
Trade Name | |
Synonyms | DUP 785|DUP785|DUP-785|NSC368390|NSC-368390|NSC 368390|Bipenquinate |
Drug Descriptions |
Brequinar (DUP 785) is a small molecule that selectively inhibits the activity of Dihydroorotate dehydrogenase (DHODH), potentially resulting in increased myeloid differentiation and decreased tumor burden (PMID: 27641501, PMID: 32525770). |
DrugClasses | |
CAS Registry Number | 96187-53-0 |
NCIT ID | C1560 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Brequinar | Brequinar | 0 | 1 |