anti-GPC3-IL15-iC9-expressing CAR T-cells
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| Drug Name | anti-GPC3-IL15-iC9-expressing CAR T-cells |
| Trade Name | |
| Synonyms | CATCH T-cells|AGAR T-cells|CATCH T cells|GO CART T-cells |
| Drug Descriptions |
anti-GPC3-IL15-iC9-expressing CAR T-cells are autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting GPC3, and co-express IL15 and inducible caspase 9 (iC9), which potentially induce antitumor activity (PMID: 39604730). |
| DrugClasses | GPC3 Immune Cell Therapy 8 |
| CAS Registry Number | NA |
| NCIT ID | C185176 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| anti-GPC3-IL15-iC9-expressing CAR T-cells | anti-GPC3-IL15-iC9-expressing CAR T-cells | 0 | 3 |
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