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Therapy Name | anti-GPC3-IL15-iC9-expressing CAR T-cells |
Synonyms | |
Therapy Description |
anti-GPC3-IL15-iC9-expressing CAR T-cells are autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting GPC3, and co-express IL15 and inducible caspase 9 (iC9), which potentially induce antitumor activity (PMID: 39604730). |