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Drug Name AMG 427
Trade Name
Synonyms AMG-427|AMG427|BiTE Antibody AMG 427|Anti-FLT3 x Anti-CD3 BiTE AMG 427
Drug Descriptions

AMG 427 is a bi-specific T-cell engager (BiTE) antibody that binds to FLT3 and CD3, which activates cytotoxic T-lymphocytes against tumor cells expressing FLT3, potentially resulting in increased death of FLT3-expressing tumor cells (NCI Drug Dictionary).

DrugClasses CD3 Antibody 99 FLT3 Antibody 5
CAS Registry Number NA
NCIT ID C156399

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AMG 427 AMG 427 0 1


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