AMG 427
Drug Detail
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| Drug Name | AMG 427 |
| Trade Name | |
| Synonyms | AMG-427|AMG427|BiTE Antibody AMG 427|Anti-FLT3 x Anti-CD3 BiTE AMG 427 |
| Drug Descriptions |
AMG 427 is a bi-specific T-cell engager (BiTE) antibody that binds to FLT3 and CD3, which activates cytotoxic T-lymphocytes against tumor cells expressing FLT3, potentially resulting in increased death of FLT3-expressing tumor cells (NCI Drug Dictionary). |
| DrugClasses | CD3 Antibody 119 FLT3 Antibody 5 |
| CAS Registry Number | NA |
| NCIT ID | C156399 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AMG 427 | AMG 427 | 0 | 1 |
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