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Drug Name | Tuspetinib |
Trade Name | |
Synonyms | HM-43239|HM 43239|HM43239 |
Drug Descriptions |
Tuspetinib (HM43239) inhibits both wild-type and mutant FLT3, resulting in decreased activation of downstream signaling, and potentially leading to increased apoptosis and decreased proliferation of tumor cells (Cancer Res 2019;79(13 Suppl):Abstract nr 1293). |
DrugClasses | FLT3 Inhibitor 69 |
CAS Registry Number | 2294874-49-8 |
NCIT ID | C165254 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Tuspetinib | Tuspetinib | 4 | 1 |
Tuspetinib + Venetoclax | Tuspetinib Venetoclax | 0 | 1 |