JSI-1187
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| Drug Name | JSI-1187 |
| Trade Name | |
| Synonyms | JSI-1187-01|JSI1187|JSI 1187 |
| Drug Descriptions |
JSI-1187 is a small molecule inhibitor of Erk1/2 that also results in decreased phosphorylation of Rsk1, and may lead to inhibition of cell proliferation and tumor growth inhibition (Cancer Res 2020;80(16 Suppl):Abstract nr 4188). |
| DrugClasses | ERK Inhibitor (pan) 21 |
| CAS Registry Number | NA |
| NCIT ID | C174203 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Dabrafenib + JSI-1187 | Dabrafenib JSI-1187 | 1 | 1 |
| JSI-1187 | JSI-1187 | 2 | 1 |
| JSI-1187 + Sotorasib | JSI-1187 Sotorasib | 0 | 0 |
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