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| Drug Name | Sotorasib |
| Trade Name | Lumakras |
| Synonyms | AMG 510|AMG510|AMG-510|Lumykras |
| Drug Descriptions |
Lumakras (sotorasib) is small molecule inhibitor that selectively targets KRAS G12C and inhibits downstream signaling, which may lead to growth inhibition of tumors harboring KRAS G12C (PMID: 31666701). Lumakras (sotorasib) is FDA approved for use in patients with locally advanced or metastatic non-small cell lung cancer harboring KRAS G12C who have received one or more prior therapy (FDA.gov). |
| DrugClasses | KRAS G12C inhibitor 34 |
| CAS Registry Number | 2252403-56-6 |
| NCIT ID | C154287 |
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