Pirfenidone
Drug Detail
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| Drug Name | Pirfenidone |
| Trade Name | |
| Synonyms | Deskar |
| Drug Descriptions |
Pirfenidone is an antifibrotic agent, which potentially activates BMP pathway, and inhibits AKT and MAPK downstream signaling, thereby reducing the proliferation and migration of tumor cells (Cancer Res 2018;78(13 Suppl):Abstract nr LB-014). |
| DrugClasses | |
| CAS Registry Number | 53179-13-8 |
| NCIT ID | C2635 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Atezolizumab + Pirfenidone | Atezolizumab Pirfenidone | 0 | 1 |
| Carboplatin + Paclitaxel + Pirfenidone | Carboplatin Paclitaxel Pirfenidone | 0 | 1 |
| Carboplatin + Pemetrexed Disodium + Pirfenidone | Carboplatin Pemetrexed Disodium Pirfenidone | 0 | 1 |
| Cisplatin + Pirfenidone | Cisplatin Pirfenidone | 0 | 0 |
| Pirfenidone | Pirfenidone | 0 | 0 |
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