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Drug Name | Pirfenidone |
Trade Name | |
Synonyms | Deskar |
Drug Descriptions |
Pirfenidone is an antifibrotic agent, which potentially activates BMP pathway, and inhibits AKT and MAPK downstream signaling, thereby reducing the proliferation and migration of tumor cells (Cancer Res 2018;78(13 Suppl):Abstract nr LB-014). |
DrugClasses | |
CAS Registry Number | 53179-13-8 |
NCIT ID | C2635 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + Pirfenidone | Atezolizumab Pirfenidone | 0 | 1 |
Carboplatin + Paclitaxel + Pirfenidone | Carboplatin Paclitaxel Pirfenidone | 0 | 1 |
Carboplatin + Pemetrexed Disodium + Pirfenidone | Carboplatin Pemetrexed Disodium Pirfenidone | 0 | 1 |
Cisplatin + Pirfenidone | Cisplatin Pirfenidone | 0 | 0 |
Pirfenidone | Pirfenidone | 0 | 0 |