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Drug Name DRP-104
Trade Name
Synonyms DRP 104|DRP104|Sirpiglenastat
Drug Descriptions

Sirpiglenastat (DRP-104) is the prodrug form of glutamine antagonist, which potentially modulates immune response and inhibits tumor growth (J Immunother Cancer. 2019; 7(Suppl 1): 282, Abs nr: P497).

DrugClasses
CAS Registry Number 2079939-05-0
NCIT ID C174038

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + DRP-104 Atezolizumab DRP-104 0 1
DRP-104 DRP-104 0 1
DRP-104 + Durvalumab DRP-104 Durvalumab 0 1
DRP-104 + unspecified PD-1 antibody DRP-104 unspecified PD-1 antibody 0 0
DRP-104 + unspecified PD-L1 antibody DRP-104 unspecified PD-L1 antibody 0 0


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