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Drug Name | HMPL-306 |
Trade Name | |
Synonyms | HMPL 306|HMPL306 |
Drug Descriptions |
HMPL-306 specifically inhibits mutant IDH1/2, resulting in decreased conversion of alpha-ketoglutarate into 2-hydroxyglutarate, and potentially leading to inhibition of of IDH1/2 mutant tumor cell proliferation (NCI Drug Dictionary). |
DrugClasses | IDH Inhibitor (Pan) 3 |
CAS Registry Number | NA |
NCIT ID | C175602 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
HMPL-306 | HMPL-306 | 3 | 2 |